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New Drug Trial for People with High Blood Pressure
Protocol: STUDY00007403
Full Title
A randomized, double-blind, placebo-controlled, parallel arm, multicenter, phase 2 study to evaluate the efficacy and safety of lorundrostat in subjects with uncontrolled hypertension on a standardized medication regimen
Description
The University at Buffalo (UB) Department of Medicine is recruiting adults with hypertension (high blood pressure) for a clinical trial. The goal of the study is to test the safety and effectiveness of a new medication (Lorundrostat) for people with high blood pressure that is not well controlled.

Participants be enrolled in the study for about 3 months and will complete several study visits. They will be randomly assigned (which happens by chance, like flipping a coin) to one of two groups: (1) will take the study medicine and 2-3 high blood pressure medications or (2) will take a placebo (which looks like the study pill but contains no active medicine) and 2-3 high blood pressure medications. They will also complete physical exams and lab tests. Participants will be paid $50 for each study visit.
Compensation: Yes
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Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Eligibility
Adults 18 years or older Have been diagnosed with hypertension (high blood pressure) that is not well controlled
Age Group: Adults
Principal Investigator: JOSEPH IZZO
ClinicalTrials.gov: Open Study
Contact(s)
KELLEY CAROZZOLO (Bilson)
kjc28@buffalo.edu
+1 716-898-5653
PETER OSMOND
pjosmond@buffalo.edu
+1 716-898-5234
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