This study is being done to see if the Buffalo Concussion Physical Exam and the Tele-Brain Injury Screen can be safely used to identify brain injury and its impact on functioning in female survivors who have experienced intimate partner violence. The Buffalo Concussion Physical Exam is a non-invasive physical exam that examines neck/head area for any discomfort. This exam also tests standing balance and the ability to follow movements with eyes. The Tele-Brain Injury Screen tells us how individuals suspected of brain injury are feeling and whether the way they are feeling is interfering with their functioning. In essence, we want to understand if intimate partner violence could result in brain injury. We also want to understand the effects of brain injury on daily functioning and social functioning. Read More

18-60 years old
Proficient in English
Physical injury to head/neck/face or strangulation injury due to partner abuse within the past year
Reports of physical abuse (e.g., being thrown against an object, partner initiated fall resulting in head injury or any other reports of physical abuse resulting in whiplash injury) by an intimate partner within the past year
Phys...

This survey study examines how transgender and gender nonconforming individuals have experienced oral healthcare, how accessible such care is to them, and how they feel about receiving it. Read More

18 or greater years of age
self-identify as transgender or gender nonconforming

This is a study to evaluate the efficacy of Chemo Mouthpiece® in minimizing patient-reported symptoms associated with oral mucositis in cancer patients receiving chemotherapy. The Chemo Mouthpiece(R) is a novel device to make it easier to deliver cryotherapy (ice chips). Read More

Aged 18-80 years
Planned to receive at least 2 cycles of infused stomatotoxic chemotherapy regimens
Be willing and able to complete all study-related activities

An early feasibility study to evaluate the safety and efficacy of Delphi Revascularization device for clot retrieval. This is for hospital patients with Anterior circulation ischemic stroke. Up to 8hrs of symptom onset or last known well time. Read More

At least 18 years of age at time of consent;
The patient or patient’s LAR has signed and dated an ICD using the Institutional Review Board (IRB) and Medtronic Approved ICD and agrees to comply with protocol requirements. Health Insurance Portability and Accountability Act of 1996 (HIPAA) authorization has been provided and signed by the patient or patient’s LAR
Has baseline N...

This study enrolls children and adults with skin conditions such as Atopic Dermatitis (eczema). The purpose of this study is to learn more about people who have been diagnosed with these conditions, including information about their health and the medications they take to manage their disease. Specifically, we want to understand how different treatments may affect the health of some patients differently than others. Read More

Adults or children.
Being prescribed medical therapy for atopic dermatitis.

Study will assess adult participants for gum disease and bacteria in the mouth. The dental exams are the same exams that normally take place in dentist’s office. Saliva and plaque will be collected from participants. Visits will be every 2 weeks or every month. Study lasts 10-12 months. Read More

At least 25 years old
At least sixteen (16) teeth
To be determined at Screening Visit: Presence of at least 4 sites (anterior or posterior) with probing pocket depths (PD) > 5 mm and < 6 mm and concomitant clinical attachment loss.
To be determined by testing subgingival plaque after the Screening Visit: Have detectable Pg in subgingival plaque as assessed by PCR (we will take sampl...

Participants will be asked questions about a new cognitive processing test (how fast they can think). This study involves a single visit which takes about 20-minutes at the Conventus Medical Center in Buffalo. 50 multiple sclerosis patients and 50 healthy people will be enrolled. Read More

Physician established diagnosis of multiple sclerosis
18 years of age or older
Able to read and speak English
Not pregnant

Study to evaluate reducing worry, anxiety, and stress in underserved communities highly impacted by the COVID-19 pandemic. Mindfulness Based Stress Reduction programs (meditation, breathing and movement) will be delivered via video / teleconference or a smart phone APP. The study lasts approximately 21 weeks. Read More

Inclusion:
(1) age 18 years and older
(2) a baseline score ≥26 (clinically significant worry) on the Penn State Worry Questionnaire-Abbreviated
(3) fluency in English
(4) reside in one of the underserved, census-identified primarily African American communities in Buffalo, NY
Exclusion:
(5) severe depression
(6) active suicidal intent
(7) DSM-V diagno...

Emergency department patients or adult companions of pediatric emergency department patients will take an anonymous survey. This survey will be used to determine the rate of Covid19 vaccinations in emergency rooms. Read More

Emergency Department patients or their adult companions

This study enrolls adults who have tested positive for COVID-19 and are currently hospitalized at Buffalo General Hospital or Millard Fillmore Hospital. The purpose is to learn whether immune study drugs that target inflammation can help with symptoms and recovery from COVID-19. 75% of the participants will receive study drug and 25% will receive placebo (no active ingredients). Neither the doctors or you will know which study drug or placebo you will receive. The study drug will either be : one time infliximab (Remicade) infusion in vein, one time abatacept (Orencia) infusion in vein, or 28 days of cenicriviroc (CVC) tablets. Most participants will also receive the anti-viral Remdesivir infusion in vein for maximum of 10 days. The study will last for about 60 days. Read More

Admitted to Buffalo General or Millard Fillmore Suburban or awaiting admission in the ED with symptoms suggestive of COVID-19.
Male or non-pregnant female adults ≥18 years of age at time of enrollment.
Has laboratory-confirmed (within 14 days prior to enrollment) SARS-CoV-2 infection as determined by PCR or other commercial or public health assay in any specimen.
Ongoing illne...