Search and volunteer to participate in these available studies at UB. Your participation in research doesn't just benefit you, it helps advance healthcare for our entire community.

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Showing 1 - 10 of 301 Clinical Trials
Description:
This study enrolls people who have Mitral Regurgitation (MR) who will be having mitral valve surgery. The purpose of this study is to learn about the effectiveness of the MitraClip™ system for treating patients who are candidates for Mitral Valve (MV) repair surgery. We will compare the MitraClip™ system to MV repair surgery which is the current standard of care for this condition. Read More
Eligibility:
-Adults age 75+ (OR if younger than 75 years, then has other conditions that make them eligible for the study).
-Diagnosed with severe mitral regurgitation.
-Your care team has confirmed that your mitral valve anatomy is suitable for percutaneous repair with the MitraClip device.
Contact(s)
ROBIN STEIN
rmstein3@buffalo.edu
+1 716-888-4859
Description:
This study enrolls people who have suffered a stroke in the past 24 hours. The purpose of this study is to learn if a patient can benefit from a clot removal procedure if they have a stroke scale of 5 or lower. Read More
Eligibility:
-Adults ages 18+
-Diagnosed with acute ischemic stroke and have an objective neurological deficit.
Contact(s)
JENNIFER GAY
jgay@ubns.com
+1 716-888-4811
Description:
This clinical study investigates a new treatment for prostate cancer. ODM-208 (CYP11A1 inhibitor) is the oral study medication that will be taken together with oral glucocorticoid (dexamethasone) and mineralocorticoid (fludrocortisone) replacement therapy. The purpose of this study is to find a safe and effective dose of ODM-208 for the treatment of prostate cancer. The purpose of this study is also to use the results of this study to support development programs of CYP11A1 inhibitors in prostate cancer and other relevant indications. Read More
Eligibility:
1) Males greater than or equal to 18 years. 2) Metastatic disease documented either by a positive bone scan, CT, PET/CT or MRI scan 3) Treatment with at least 1 line of taxane-based chemotherapy in castration-sensitive prostate cancer (CSPC) or in CRPC
Contact(s)
Deonna Coleman
dc84@buffalo.edu
Description:
Eligibility:
-Adults ages 18-80
-Has a single unruptured target intracranial aneurysm (IA) located on the internal carotid artery (ICA) or its branches.
Contact(s)
JENNIFER GAY
jgay@ubns.com
+1 716-888-4811
Description:
Participants 1-24 months old at Oishei Children's Hospital Emergency Deparment (ED) with suspected Bronchiolitis may be eligible for this study. Once enrolled, participants will undergo two carbon dioxide measurements, first will be done upon ED arrival at the Triage room, and the second one will be done upon ED discharge at patient's private room. Otherwise, participant will receive routine clinical care. Read More
Eligibility:
Children ages 1-24 months old.
Have respiratory signs and symptoms and suspected bronchiolitis.
Contact(s)
Haiping Qiao
hqiao@buffalo.edu
+1 716-323-0055
Description:
The purpose of this study is to identify promising treatments and compare them to determine which are most effective and then move into studies that can prove their effectiveness. The study will be conducted at up to 40 sites throughout the US with 200 patients being enrolled. Participants will receive one of several investigational products and then be evaluated for outcomes related to their overall improvement. They will be monitored at all times for safety and any adverse reactions to the products. Read More
Eligibility:
Admitted to a hospital with symptoms suggestive of COVID-19 and requires ongoing medical care.
Subject (or legally authorized representative) provides informed consent prior to initiation of any study procedures.
Subject (or legally authorized representative) understands and agrees to comply with planned study procedures.
Male or non-pregnant female adult ≥18 years of age at t...
Contact(s)
Judith Wilkins
jwilkins@ecmc.edu
+1 716-898-5066
Description:
This study enrolls children and adults with skin conditions such as Atopic Dermatitis (eczema). The purpose of this study is to learn more about people who have been diagnosed with these conditions, including information about their health and the medications they take to manage their disease. Specifically, we want to understand how different treatments may affect the health of some patients differently than others. Read More
Eligibility:
Adults or children.
Being prescribed medical therapy for atopic dermatitis.
Contact(s)
HEATHER LEHMAN
hkm@buffalo.edu
+1 716-878-7105
Description:
Participants will be asked questions about a new cognitive processing test (how fast they can think). This study involves a single visit which takes about 20-minutes at the Conventus Medical Center in Buffalo. 50 multiple sclerosis patients and 50 healthy people will be enrolled. Read More
Eligibility:
Physician established diagnosis of multiple sclerosis
18 years of age or older
Able to read and speak English
Not pregnant
Contact(s)
Michael Jaworski
mgjawors@buffalo.edu
Description:
This study enrolls adults who have tested positive for COVID-19 and are currently hospitalized at Buffalo General Hospital or Millard Fillmore Hospital. The purpose is to learn whether immune study drugs that target inflammation can help with symptoms and recovery from COVID-19. 75% of the participants will receive study drug and 25% will receive placebo (no active ingredients). Neither the doctors or you will know which study drug or placebo you will receive. The study drug will either be : one time infliximab (Remicade) infusion in vein, one time abatacept (Orencia) infusion in vein, or 28 days of cenicriviroc (CVC) tablets. Most participants will also receive the anti-viral Remdesivir infusion in vein for maximum of 10 days. The study will last for about 60 days. Read More
Eligibility:
Admitted to Buffalo General or Millard Fillmore Suburban or awaiting admission in the ED with symptoms suggestive of COVID-19.
Male or non-pregnant female adults ≥18 years of age at time of enrollment.
Has laboratory-confirmed (within 14 days prior to enrollment) SARS-CoV-2 infection as determined by PCR or other commercial or public health assay in any specimen.
Ongoing illne...
Contact(s)
Janice Wolfman
janicewo@buffalo.edu
Description:
We are doing this study to find out if there is a connection between poor sleep in children with cystic fibrosis and the development of diabetes. Cystic Fibrosis patient and the parent will complete a single 10 minute survey about how CF patient sleeps. The study team will collect some information about the child’s health including the results of an oral glucose tolerance test. Read More
Eligibility:
Inclusion criteria include having cystic fibrosis, being 10 years old or older and either having an oral glucose tolerance test (a screen for CF-related diabetes) in 2020 or planning to have one in 2021. Exclusion criteria include a history of long-standing CF-related diabetes, liver failure or liver transplant or receipt of steroids within 6 weeks prior to the oral glucose tolerance test.
Contact(s)
AMANDA HASSINGER
albrooks@buffalo.edu
+1 716-878-7442
Showing 1 - 10 of 301 Clinical Trials
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