Search and volunteer to participate in these available studies at UB. Your participation in research doesn't just benefit you, it helps advance healthcare for our entire community.

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Showing 11 - 20 of 331 Clinical Trials
Description:
This clinical trial is seeking to enroll patients with curved spines or other anatomic spinal problems. The goal of this trial is to determine whether placing a device, called iFuse-3D, into the sacrum and ilium (pelvis) bone during multilevel spine fusion (MLF) surgery provides benefits compared to not using this device. During MLF surgery, a spine surgeon places rods and screws in the spine in an attempt to straighten the spine and correct other spinal problems. The surgeon also places screws into the sacrum and pelvis bone. This may result in a decrease in pain and a restoration of the normal curvature of the spine. This is a multicenter trial with up to 35 hospitals in the US, Europe, and Australia. This study hopes to enroll 220 patients. If you participate, the study requires you to participate for two years with in-person visits between 2-6 weeks post-operation and at 6, 12 and 24 months. Read More
Eligibility:
1. Age 21-75 at time of screening
2. Patient scheduled for multilevel (4 or more levels) spinal fusion surgery with planned fixation to the pelvis using S2AI screws
3. Patient has signed study-specific informed consent form
4. Patient has the necessary mental capacity to participate and is physically able to comply with study protocol requirements
Contact(s)
Tia Warrick
tiawarri@buffalo.edu
Description:
The goal of the UB Eating Among Teens Study (UB EATS) is to measure eating behaviors and neighborhood and household factors in 11 - 14-year-olds over the course of 3 years. Participation involves 7 visits to the UB Nutrition and Health Research Lab on South Campus over the 3-year period to answer questionnaires and eat snack foods. Low and middle-income families are encouraged to apply. Read More
Eligibility:
- Adolescents aged 11 - 14 years - BMI percentile >5th or < 97th - size-adjusted household income <250% of US poverty line - no medical conditions or medications that impact appetite - no allergies to study foods - at least a moderate liking of one or more of the study foods - identification of a study food that is consumed < 3 times per week - planning to live in the Western New York area...
Contact(s)
JENNIFER TEMPLE
jltemple@buffalo.edu
+1 716-829-5593
Description:
A hot work environment can lead to fatigue, hyperthermia, and dehydration, which may increase injury risk and reduce productivity. The goal of this study is to learn more about the body’s response to repeated days of working in a hot and humid environment. Participation will involve 7 visits to the UB South Campus for repeated days of 8-hour periods of sitting or performing moderate-high intensity work in a hot and humid room. Read More
Eligibility:
Males and females ages 18-39
Contact(s)
Riana Pryor
rpryor@buffalo.edu
Description:
The goal of this study is to evaluate the safety, effectiveness and tolerability of a drug compound (AVP- 786) for the treatment of agitation associated with Alzheimer’s Disease. Alzheimer’s Disease causes loss of brain cells and problems with memory, thinking and behavior. Agitated behaviors, such as irritability and restlessness, physical and verbal aggression, and pacing and wandering are major problems in this condition, can be difficult to manage, and can impact your quality of life. AVP-786 is targeted at treating your agitation behaviors. Caregivers are being asked to take part in this research study because the participants may require assistance to complete study procedures and/or attend study visits. Participation in this study will last for approximately 20 weeks and include site visits throughout the study. Read More
Eligibility:
Patients 50 to 90 years of age (inclusive) with clinically significant, moderate-to-severe agitation for at least 2 weeks prior to screening that interferes with daily routine per the Investigator's judgment, and who require pharmacotherapy for the treatment of agitation per the Investigator's judgment after an evaluation of reversible factors and a course of nonpharmacological interventions. A...
Contact(s)
CONNIE BRAND
conniebr@buffalo.edu
+1 716-323-0549
Description:
This study looks at the safety and efficacy of the combination of Pembrolizumab, Carboplatin, & Paciltaxel for patients with incurable head and neck cancer that has returned after being treated or has spread to other body parts. The study will take place at ECMC and can last 2-3 years. Read More
Eligibility:
-Has histologically or cytologically-confirmed diagnosis of recurrent / metastatic head and neck squamous cell carcinoma (HNSCC) that is considered incurable by local therapies.
-Has not had prior systemic therapy administered in the recurrent or metastatic setting. Systemic therapy, which was completed more than 6 months prior to signing consent, if given as part of multimodal treatment f...
Contact(s)
JAMES ZEMER
jameszem@buffalo.edu
+1 716-645-2521
Description:
This study enrolls people who have come to a participating Emergency Department to be treated for a headache. The purpose of this study is to learn more about whether two specific combinations of tests rules out a serious cause of headaches called aneurysmal subarachnoid hemorrhages (sometimes called “brain bleeds”). Read More
Eligibility:
-Ages 18+
-Presenting to a participating Emergency Department with a headache
Description:
We are looking for adults ages 18-40 for this study. We are looking for people in general good health and also people who have had a history of blast exposure and blunt head trauma. The purpose of this study is to learn more about balance in people with a history of blast exposure and blunt head trauma compared to healthy people. You will participate in this study for one session that lasts about 3 hours. During the study you will complete balance, vision, and stability tests in our lab. Study visit takes place in the Department of Rehabilitation Science lab at UB's South Campus. Participants will be compensated. Read More
Eligibility:
-Adults ages 18-40.
-Generally healthy OR have had a history of impact brain injury/head trauma in past ten years.
Contact(s)
VIJAYA PRAKASH KRISHNAN MUTHAIAH
vijayapr@buffalo.edu
+1 716-829-5291
Description:
This study enrolls students who participate in the after-school program at a local Buffalo community location. The purpose of this study is to look at reading and literacy skills after a computer based newsletter program. Read More
Eligibility:
-Children ages 10-13.
-Must be in the after-school program at a participating local Buffalo community center in grades 6-8.
-Must have access to a computer: laptop, Chromebook, or desktop with the capability to download Zoom.
-Must have internet access at home or center.
Description:
This study enrolls older adults with Alzheimer’s Disease (AD). The purpose of the study is to learn whether the study drug, GV-971, can help the thinking (cognition) and functioning of people with AD. Read More
Eligibility:
-Adults ages 50-85.
-Mild to moderate Alzheimer's Disease.
-Please contact our team to learn whether you or your loved one may be a good match for this study.
Contact(s)
CONNIE BRAND
conniebr@buffalo.edu
+1 716-323-0549
Description:
This study is enrolling patients with pemphigus (vulgaris or foliaceus), a condition where the immune system attacks the skin and/or mucosa (the most superficial layer that lines body cavities and passages, for example, in your mouth). Participants are invited to take place in this study if they are newly diagnosed with pemphigus or have experienced a flareup. The goal of the study is to investigate the safety, effectiveness and tolerability of a drug compound (efgartigimod PH20 SC) in adult patients aged 18 to 80 years with pemphigus. Read More
Eligibility:
Patient has a clinical diagnosis of pemphigus vulgaris or pemphigus foliaceus which has been confirmed by cutaneous histology, positive direct immunofluorescence (IF), and positive indirect IF and/or ELISA.
Contact(s)
CATHERINE WRONA
wrona@buffalo.edu
+1 716-888-4713
Showing 11 - 20 of 331 Clinical Trials
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