-Adults ages 18-80
-Has a single unruptured target intracranial aneurysm (IA) located on the internal carotid artery (ICA) or its branches.

This study is being done to see if the Buffalo Concussion Physical Exam and the Tele-Brain Injury Screen can be safely used to identify brain injury and its impact on functioning in female survivors who have experienced intimate partner violence. The Buffalo Concussion Physical Exam is a non-invasive physical exam that examines neck/head area for any discomfort. This exam also tests standing balance and the ability to follow movements with eyes. The Tele-Brain Injury Screen tells us how individuals suspected of brain injury are feeling and whether the way they are feeling is interfering with their functioning. In essence, we want to understand if intimate partner violence could result in brain injury. We also want to understand the effects of brain injury on daily functioning and social functioning. Read More

18-60 years old
Proficient in English
Physical injury to head/neck/face or strangulation injury due to partner abuse within the past year
Reports of physical abuse (e.g., being thrown against an object, partner initiated fall resulting in head injury or any other reports of physical abuse resulting in whiplash injury) by an intimate partner within the past year
Phys...

This survey study examines how transgender and gender nonconforming individuals have experienced oral healthcare, how accessible such care is to them, and how they feel about receiving it. Read More

18 or greater years of age
self-identify as transgender or gender nonconforming

This is a study to evaluate the efficacy of Chemo Mouthpiece® in minimizing patient-reported symptoms associated with oral mucositis in cancer patients receiving chemotherapy. The Chemo Mouthpiece(R) is a novel device to make it easier to deliver cryotherapy (ice chips). Read More

Aged 18-80 years
Planned to receive at least 2 cycles of infused stomatotoxic chemotherapy regimens
Be willing and able to complete all study-related activities

The University at Buffalo (UB) School of Dental Medicine is looking for volunteers to join a gum disease study. The study aims to learn more about how harmful bacteria grow in the mouth and cause periodontal (gum) disease. We are interested in Porphyromonas gingivalis (P. ginivalis), a pathogen involved in gum disease. Read More

Adults aged 25 years or older Have at least 16 natural teeth Have the bacterium Porphyromonas gingivitis in their mouth Have gum disease (which will be determined by study staff) Do not wear braces or other orthodontic equipment Have not had periodontal treatment or surgery in the past year Not currently pregnant

Participants will be asked questions about a new cognitive processing test (how fast they can think). This study involves a single visit which takes about 20-minutes at the Conventus Medical Center in Buffalo. 50 multiple sclerosis patients and 50 healthy people will be enrolled. Read More

Physician established diagnosis of multiple sclerosis
18 years of age or older
Able to read and speak English
Not pregnant

Study to evaluate reducing worry, anxiety, and stress in underserved communities highly impacted by the COVID-19 pandemic. Mindfulness Based Stress Reduction programs (meditation, breathing and movement) will be delivered via video / teleconference or a smart phone APP. The study lasts approximately 21 weeks. Read More

Inclusion:
(1) age 18 years and older
(2) a baseline score ≥26 (clinically significant worry) on the Penn State Worry Questionnaire-Abbreviated
(3) fluency in English
(4) reside in one of the underserved, census-identified primarily African American communities in Buffalo, NY
Exclusion:
(5) severe depression
(6) active suicidal intent
(7) DSM-V diagno...

This study enrolls men with prostate cancer. The purpose of this study is to compare using radium-223 and docetaxel chemotherapy treatment vs. using docetaxel alone in men with Metastatic Castration-Resistant Prostate Cancer (mCRPC). Radium223 has been FDA approved to treat men with prostate cancer that has spread to the bone, but it has not been approved for men with cancer that has spread to soft tissue or in combination with the chemotherapy drug docetaxel. Read More

Adults ages 18+.
Males with progressive Metastatic Prostate Cancer.
Have 2+ bone lesions.

This study enrolls adults diagnosed with head and neck cancer who have plans to complete chemoradiotherapy. The purpose of this study is to learn the best timing for feeding tube placement and speech therapy to create the best quality of life for patients. Read More

Adults ages 18+.
Patients with Head and Neck Cancer being treated at ECMC and Cancer Care WNY.
Patients planning to receive concurrent chemo-radiation therapy.

This study enrolls adults who have had a brain hemorrhage within the last 7 days. The purpose of the study is to learn whether it is better to keep taking or stop taking the medication statin after having a brain bleed. Read More

Adults ages 50+.
Have had bleeding in the brain (brain hemorrhage) within the last 7 days.
Were taking a statin drug.
People who may be eligible for this study will be contacted by study staff directly. Eligible participants will be inpatients of Buffalo General/Gates Vascular Institute.