Children's Influenza Study at Oishei Children's Hospital
Protocol: STUDY00002824
Full Title
Comparison of B cell responses in Kawasaki disease to viral illnesses.
Description
We are looking for children with common infections for a study. The purpose of the study is to compare the cells of children with common infections like the flu to to those with a febrile disorder called Kawasaki disease. This will help us see how the immune system responds differently to different illnesses.

Your child will be asked to be in the study during their hospitalization and then on two follow-up visits at around 2 weeks after the illness began and 4-8 weeks after the illness began. Your child will give blood samples while in the study. Study visits take place at Oishei Children’s Hospital and at our office at 875 Ellicott Street, Buffalo NY 14203.

Participants will be compensated.

Technical Description

Response: The purpose is to find antibodies specific to Kawasaki Disease (KD). These potentially can be used as advanced diagnostics or to identify the etiology of KD, the leading cause of childhood coronary vasculitis.
Specific aim 1 (SA1): I will characterize and compare circulating B cell subsets during acute Kawasaki presentation versus other febrile illnesses.
Specific aim 2 (SA2): Utilizing advanced antibody sequencing, I will characterize the specific antibody responses during acute Kawasaki presentation.

Keyword: flu or adenovirus, ER, Inpatient
Compensation: Yes
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Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Eligibility
Children age 6 months - 6 years old
Children must be in the Emergency Department or inpatient ward of John R. Oishei Children's Hospital with a positive screen for influenza or adenovirus

Also Enrolling:

Children (<18 years old) under consideration for Kawasaki disease
Age Group: Children
Principal Investigator: MARK HICAR
Contact(s)
MARK HICAR
markhica@buffalo.edu
+1 716-323-0152
Want to Learn More?
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.