Head and Neck Surgery Study
Protocol: STUDY00003370
Full Title
Epithelial Differentiation of Tissues of the Oral Cavity.
Description
This study enrolls adults who are having a head or neck surgery that will remove tissue that makes saliva. This research is being done to gain a better understanding of the tissue that makes saliva (salivary gland tissue).

We will keep a small amount of normal (healthy) salivary gland tissue from you that would otherwise be THROWN away as a result of your surgical procedure. This will not change or alter your surgical procedure in any way. Salivary tissue will be kept five years after the close of this study (about 10 years total). Study takes place at ECMC Department of Head and Neck Surgery (Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215).

No compensation available.

Technical Description

This study is a bio-specimen analysis of salivary gland tissues, that would other wise be discarded during standard of care, to study the transcriptional regulatory mechanisms governing the development and differentiation of epithelial rich tissues such as the salivary gland. We plan to perform RNA-seq, scRNA-seq, and establish cells lines and perform immunostaining on discarded salivary gland tissues.
Compensation: No
Eligibility
-Adults ages 18+
-Come to the ECMC Department of Head and Neck Surgery for a procedure involving removal of salivary tissue.
Age Group: Adults
Principal Investigator: JENNIFER FRUSTINO
Contact(s)
JAMES ZEMER
jameszem@buffalo.edu
+1 716-645-2521
Want to Learn More?
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.