A Prospective Study to Validate the Expanded Timed Get-Up-and-Go in a Population with Multiple Sclerosis at Varying Levels of Disability
Description
This study enrolls people with MS. The purpose of the study is to learn more about a whether a certain timed performance test is valid for MS patients.
You will participate in two sessions for this study over a one week timeframe. Each visit takes about 20-30 minutes. This study takes place at UBMD Neurology clinic (1001 Main Street, Buffalo, NY 14203) or Dr. Susan Bennett’s office (2075 Sheridan Drive, Kenmore, NY 14223).
Participants will be compensated.
Technical Description
(CSR # 171233633751) The Expanded Timed Get-Up-and-Go (ETGUG) is an objective, continuous measure of balance and walking ability. It is correlated with current disability measures, but it more highly predictive of falls and is more strongly associated with atrophy and decreased gray matter volume on MRI. We propose to conduct a validation study of the ETGUG among persons with multiple sclerosis (pwMS) with varying levels of disability, as measured by the Kurtzke Expanded Disability Status Scale (EDSS), and to determine its correlation with falls. An additional aim will be to evaluate the clinically meaningful change in the ETGUG over 2 years, compared with the EDSS, Timed 25 Feet Walk (T25FW), Multiple Sclerosis Functional Composite (MSFC) and patient-reported outcomes (PROs).
Compensation:
No
Eligibility
Adults ages 18-40.
Generally healthy.
No history of abnormal hearing or balance.
Let us know how the study team can reach you.
If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.
