Sleep Program for Multiple Sclerosis
Protocol: STUDY00002255
Full Title
Mindfulness-based stress reduction plus sleep retraining to improve depressive symptoms among adults with multiple sclerosis
We are studying the effects of a mindfulness and sleep program on wellbeing for people with MS (multiple sclerosis). We want to compare
the effect of the program on mood, sleep, fatigue, daytime activity, and quality of life. Participants will learn and practice stress reduction
while contributing to knowledge about MS.

Participation will involve:
-Completing a mindfulness and healthy sleep program in person (at the United Way, 742 Delaware Ave. Buffalo, NY 14209)
or virtually (via a live group class on an online meeting platform- video chat equipment provided if necessary).
-Program classes once weekly for 8 weeks.
-An introductory meeting (can be completed in the comfort of your home or at UB's South Campus).
-Wearing a sleep and activity watch and keeping a sleep diary for 7 days before and after partcipating in the program.
-Refreshments will be provided at in-person classes.
-Compensation will be provided.

If you're interested in this study, please contact the study contact listed below.

Technical Description

Researchers at UB are seeking adults aged 30 to 70 who have been diagnosed with Multiple Sclerosis (MS) to compare the effects of mindfulness-based stress reduction (MBSR) plus sleep retraining (SR) to usual care. MBSR+SR will be provided on-site and virtual through Zoom, a software program, in your home.

The intervention consists of an orientation session followed by 8 weekly sessions of MBSR+SR and home mindfulness practices. People assigned to the usual care group can participate in MBSR+SR after the first group finishes.

We will ask participants who live in the Buffalo area to participant in physical measures of balance, gait, and endurance to measure changes before and after the classes. All participants will be asked to wear an actigraphy watch and complete a sleep diary for 7 days before and after participation in MBSR+SR to measure sleep and daytime activity.

Our primary aim is to compare the effect of MBSR+SR on mood, sleep, fatigue, daytime activity, and quality of life. We will also offer interviews after completion of MBSR+SR to provide information to improve the intervention for future studies. You will be compensated for your participation.

For additional questions or to obtain more information regarding this study, please contact Dr. Rebecca Lorenz at the University at Buffalo School of Nursing, Phone: 716-829-2204 or email:

Keywords: Multiple Sclerosis (MS)
Compensation: Yes
Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Ages 30-70 with Multiple Sclerosis (MS)
Can walk without a cane or walker
Can speak and understand English
Have access to a computer (if you prefer the virtual program option)
Age Group: Adults
Principal Investigator: Rebecca Lorenz
Rebecca Lorenz
+1 716-829-2204
Want to Learn More?
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email and someone will assist you.