Doctors from UB are looking for adults living with tricuspid regurgitation (TR) for a clinical trial. TR happens when there is a leaking heart valve. This occurs when the heart’s tricuspid valve does not close as it should. The blood flows backwards instead of forward with each heartbeat which may cause people to feel tired. They may also have swelling in their legs and stomach and might be unable to do as much because their heart is not working properly. Read More

-Adults 18 years or older
-Have been diagnosed with tricuspid valve regurgitation

Parkinson’s disease (PD) is a common movement disorder that results from a breakdown in the brain. It often leads to challenges with talking. However, less is known about the relationship between speaking and hearing for people with PD. Read More

-Adults 45 to 80 years old
-Are a native English speaker
-Do not use a hearing aid
-Have been diagnosed with Parkinson’s disease
-Do not have any other diagnosed neurological issues (those affecting the brain, spinal cord, or nerves)

Some adults that have heart valve replacement end up having their new valves fail. This leads them to need surgery to correct the issue. The goal of this study is to see if a new heart valve system is safe and effective for adults that have had their replacement heart valves fail. Read More

Adults 65 years or older
Have uncontrolled blood pressure

Many patients with aortic stenosis (AS) have surgery to replace the heart valve that is not working properly. However, surgical options always have higher risk than non-surgical options. Doctors are interested in developing a non-surgical way to replace heart valves in patients with AS. Read More

Adults 18 years or older
Have been diagnosed with aortic stenosis
Are in need of aortic valve replacement

Have you been diagnosed with aortic regurgitation (AR)? If so, you may be eligible for the ARTIST clinical trial. Read More

Adults 18 years or older
Have been diagnosed with moderate to severe aortic regurgitation (AR)

The University at Buffalo (UB) is looking for older adults that have uncontrolled blood pressure to join a study. The goal of this study is to see how safe and effective renal denervation procedures are in people with high blood pressure. Read More

Adults 65 years or older
Have uncontrolled blood pressure

Aortic regurgitation (AR) is a heart valve problem that happens when the aortic valve doesn’t fully close. This allows blood to leak backward into the heart. When AR becomes severe, it can cause symptoms like shortness of breath, feeling tired, dizziness, chest pain, irregular heartbeat, and swollen ankles or feet. Over time, severe, symptomatic AR can lead to heart failure. Surgery is often needed to fix or replace the valve. Read More

Adults 18 years or older
Have been diagnosed with severe aortic regurgitation (AR)

High blood pressure (BP) is a common condition that affects many adults. It causes your heart to have to work harder to pump blood throughout your body. If left untreated, it can lead to damage of blood vessels and the heart over time. This can lead to heart attack or stroke. Unfortunately, it can be challenging for adults to manage their high BP despite making lifestyle changes and taking medications. Read More

Adults 18 years or older
Have been diagnosed with high blood pressure (hypertension)
Are struggling to control their high blood pressure despite taking medication and attempting lifestyle changes

Aortic stenosis is a type of heart valve disease in which the valve is narrowed and does not open fully. This reduces or blocks blood flow from the heart to the rest of the body. Read More

Adults 18 years or older
Have had a TAVR procedure in the past that needs to be redone

Adults living with failing heart valves are at an increased risk for heart failure. In order to treat failing heart valves, many patients require open heart surgery. Researchers are interested in developing a new way to fix failing heart valves that is less invasive than open heart surgery. Read More

Adults 18 years or older
Have a bioprosthetic aortic valve that is failing and needs to be replaced
You fall in the high or greater risk category for open heart surgery