Neurocognitive, Electrophysiological and MRI Changes Associated with Low Level Laser Therapy (Photobiomodulation) in the Treatment of Traumatic Brain Injury: A Pilot Study
Protocol: STUDY00000939
Full Title
Neurocognitive, Electrophysiological and MRI Changes Associated with Low Level Laser Therapy (Photobiomodulation) in the Treatment of Traumatic Brain Injury: A Pilot Study
Description
This research is being conducted to determine if the use of Low Level Laser Therapy, also known as Photobiomodulation, can be used to help eliminate some of the symptoms caused by injury to the brain as a result of a concussion.

You will be in this research study for approximately 4 weeks. The study involves three parts: 1) An evaluation – approximately 4 hours total 2) Brief treatment sessions that occur over 2 weeks, 3) repeat evaluation to see how the treatment worked. The treatment involves sitting in a chair and having a light shined on your head at various locations. It is painless but may help heal your brain.

The study visits will be at the University at Buffalo South Campus.

Compensation is available

Technical Description

The proposed pilot project will be a critical test of the benefits of Photobiomodulation (PBM) on mild traumatic brain injury (mTBI) using sophisticated quantitative measures to track cognitive, functional, and structural changes that might result from the treatment with PBM laser exposure. Secondarily, we will be able to examine the relationship among electrophysiological measures of function, behavioral indices of information processing speed and working memory, structural measures of brain intactness, and biomarkers of injury in mTBI patients. To our knowledge, such a comprehensive approach to mTBI has not been taken previously.
Compensation: No
Eligibility
1) Recent Head Trauma;
2) Mild cognitive impairment (MCI): symptoms lasting >2 weeks but < 3 months;
3) Neurological / General Medical / Cognitive:
a. No preexisting neurologic disease (incl. seizures) other than TBI.
b. No other chronic illness that affects cognition;
c. No history of learning disability;
4) Psychiatric: No preexisting or current Axis I diagnosis other than depression;
5) Alcohol / Substance use: No history of alcohol / drug abuse or dependence, 6) Psychotropic Medications: No history or current use.
Age Group: Adults
Principal Investigator: DAVID SHUCARD
Contact(s)
THOMAS MANG
tsmang@buffalo.edu
+1 716-829-3047
Want to Learn More?
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.