A one-year randomized, double-blind, active-controlled multi-center phase 2 clinical trial to assess the safety and the anti-caries efficacy of nonfluoride dentifrices with 1.5%, 4.0% and 8.0% arginine in comparison with 0.24% sodium fluoride (1100 ppm F) dentifrice control in 10 to 14-year-old children
This study enrolls children and teens. The purpose of the study is to see which types of toothpaste give the most benefit to teeth.
In the study, your child will be randomly assigned one of four toothpastes (like pulling a number from a hat). Three will contain arginine, one will contain sodium fluoride. They will use the toothpaste and the health of their teeth will be checked at five visits during a one-year period.
Compare the efficacy of nonfluoride arginine toothpaste to sodium fluoride toothpaste in children 10-14 years of age.
Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Children ages 10-14.
Presence of second molars or evidence of erupting permanent second molars.
Good general health
Let us know how the study team can reach you.
If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email firstname.lastname@example.org and someone will assist you.