Head & Neck Cancer Patients with Trouble Swallowing
Protocol: STUDY00004554
Full Title
Comparison of High Resolution Pharyngeal Manometry (HRPM) to current standard of care as an objective measure for determining clinical care for dysphagia in a post-radiated head amp; neck cancer patient
Description
This study enrolls people who have been treated with Radiation therapy for larynx, pharynx, nasopharynx, tonsil & base of tongue cancer who have trouble swallowing. The purpose of this study is to develop a better method to collect swallow pressure information, which may replace current less precise techniques.

We expect that you will be in this research study for about 4 months. You will be randomized (like the flip of a coin) to get one of the following standards of care that you are eligible for: speech therapy alone or speech therapy + Esophageal (EGD) dilation as part of your rehabilitation treatment plan. You will complete two additional questionnaires, once during your regular appointment and again during your regular follow-up 6-12 weeks later. You will also be asked to complete a compliance checklist at your 6-12 week standard of care follow-up. Study takes place at ECMC (Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215).

Technical Description

The aim of the research is to establish High Resolution Pharyngeal Manometry (HRPM) as a diagnostic tool in determining upper esophageal sphincter (UES) dilation candidacy of post radiated heand and neck cancer patient. Establishing an objective diagnostic tool may replace current subjective and qualitative measures. These measures will improve dysphagia rehabilitation and reduce comorbidities of patients who are treated Radiotherapy (RT) for the treatment of head amp; neck cancers.
Compensation: No
Eligibility
Ages 18+.
People with the following cancers: Nasopharyngeal, Laryngeal, Oropharyngeal, Hypo-pharyngeal, Base of Tongue, & Tonsilar.
Must have completed an entire Radiotherapy cycle.
Have dysphagia (swallowing difficulties).
Must be able to undergo speech therapy alone or speech therapy + esophageal dilation dilation as part of their rehabilitation treatment plan.
Age Group: Adults
Principal Investigator: Shawn Florkowski
Contact(s)
JAMES ZEMER
jameszem@buffalo.edu
+1 716-645-2521
Want to Learn More?
Enrollment Update

Due to COVID-19, new enrollment in research studies will be greatly limited. If you are interested in a study, there may be a longer waiting period to receive a response to your inquiry. View the guidance for research participants for additional information.

Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.