Effect of vitamin D on recovery of skeletal muscle damage in females
This study enrolls women ages 18-39 who exercise regularly. The purpose of this study is to learn about the relationship between vitamin D and recovery of skeletal muscle damage in females.
You will spend a total of 6-9 hours over 6 separate occasions in our lab for this study. Throughout the study you will fill out surveys, have height, weight, and vital signs measured, provide blood draws, and have measurements on your legs. You will be randomly picked (like flipping a coin) to either take Vitamin D or a placebo for 4 weeks. The placebo looks like Vitamin D but has no active ingredients. Study takes place at UB's South Campus.
Unaccustomed exercise can damage the skeletal muscle fibers by disrupting the sarcomeres (basic contractile unit of skeletal muscle fibers), which causes a syndrome known as delayed onset muscle soreness (DOMS) in the following days. To repair the damage, the body utilizes various pathways to remove damaged proteins and remodel the muscle fibers. A number of nutritional supplements, including Vitamin D, have been reported to play a role in these processes. This study is being done to examine the relationship between Vitamin D status and recovery of skeletal muscle damage in females. The secondary objective is to observe differences in markers of delayed onset muscle soreness (DOMS) between a group that starts out as Vitamin D sufficient, and the group that is deficient and is brought up to sufficiency through supplementation.
Let us know how the study team can reach you.
If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email firstname.lastname@example.org and someone will assist you.