study for people having a salivary gland biopsy
Protocol: STUDY00004773
Full Title
Understanding molecular mechanisms of Sjogrens syndrome pathogenesis
Description
This study enrolls people who will be having a salivary gland biopsy at ECMC. The purpose of the study is to learn more about the tissue that makes saliva (salivary gland tissue).

We expect that the collection of tissue for this research study will take no longer than your scheduled surgery. We will keep a small amount of salivary gland tissue that is removed as part of the usual biopsy procedure and use it for research purposes. Study takes place at ECMC.

Technical Description

We are interested in understand molecular mechanism that drive salivary gland inflammation. Human salivary gland tissue samples form Sjogrens syndrome (SS) patients and non-SS controls will be a valuable resource to generate insights into the molecular mechanisms that mediate disease within this organ. We will use the salivary gland tissues from this study to perform specific biochemical and molecular analyses. Our objectives are to identify genes and molecular pathways and networks that are important for salivary gland pathophysiology. Long term these studies can reveal new biomarkers for diagnosis and treatment of inflammatory diseases of the salivary gland.
Compensation: No
Eligibility
Adults ages 18+.
People who need minor salivary gland biopsy for suspected Sjogren's Syndrome.
Age Group: Adults
Principal Investigator: JILL KRAMER
Contact(s)
JAMES ZEMER
jameszem@buffalo.edu
+1 716-645-2521
Want to Learn More?
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.