Due to COVID-19, new enrollment in research studies will be greatly limited.
If you are interested in a study, there may be a longer waiting period to receive a response to your inquiry.
View the guidance for research participants for additional information.
This study enrolls people who are currently hospitalized due to COVID-19. The purpose of this study is to learn about the safety and effectiveness of an investigational drug called APL-9. We want to know if this investigational drug helps patients recover from COVID-19 related lung inflammation faster. Read More
Adults ages 18+.
Confirmed COVID-19 infection.
Diagnosis of mild to moderate acute respiratory distress syndrome (ARDS) and need mechanical ventilation.
Have not been treated with convalescent plasma for COVID-19.
No evidence of kidney or liver failure.
This study enrolls adults who have been chosen to participate because they have carotid narrowing (a blockage) that may benefit from the use of the Neuroguard IEP System, a carotid stent and filter used during a medical procedure to open the blockage. Read More
-Adults ages 20-80.
-Have been diagnosed with carotid artery stenosis treatable with carotid artery stenting.
-Additional eligibility criteria apply.
This study enrolls adults who are scheduled to have an aortic valve replacement for disease the aortic valve called aortic stenosis. The Evolut PRO and Evolut PRO+ systems are FDA approved for treating aortic stenosis, so in this study we just want to collect data. The purpose of this study is to learn more about how well this device works. Read More
-Adults ages 18+.
-Have symptoms from aortic valve stenosis.
-Will be having aortic valve replacement.
This study enrolls people who have mitral regurgitation (MR). Mitral regurgitation happens when the heart’s mitral valve does not close tightly. The purpose of this trial is to evaluate a new investigational device called the Tendyne™ Mitral Valve System. The Tendyne Mitral Valve System is designed for the treatment of a diseased, damaged or malfunctioning mitral valve. This trial will collect information on how safe and effective this device is to treat a leaking mitral valve compared to the commercially available MitraClip® System. Read More
-Adults ages 18+.
-Have symptomatic, moderate-to-severe/severe mitral regurgitation (MR) or severe mitral annular calcification (MAC)
-Your medical providers have decided a transcatheter therapy is more appropriate than open surgery.
This study enrolls pregnant women who smoke cigarettes. The purpose of this study is to learn what types of smoking cessation (quit smoking) programs help women quit while also supporting breastfeeding. Read More
Adult women, ages 18+.
Currently pregnant (at 29 weeks of pregnancy or earlier).
Have smoked 1+ cigarettes per day in the past week.
Must enroll with a family support person (a partner or family member). This person must have a close relationship and frequent contacts with the pregnant woman and be willing to support breastfeeding.
This study enrolls people who are scheduled for a surgery at ECMC involving removing the tissue that makes saliva. The purpose of this study is to use tissue samples that otherwise would have been discarded to learn more about how salivary gland inflammation happens at a molecular level. We hope this will lead to new ways to diagnose and treat salivary gland inflammatory diseases. Read More
Adults ages 18+
Scheduled for a surgery at ECMC involving salivary gland excision (e.g. Neck Dissection Surgery, etc.)
Any sample of salivary gland tissue that would otherwise be discarded will be included for the study.
This study enrolls current patients who have MS. The purpose of this study is to gain a better understanding of Severely Affected Patients with MS to lead to better early identification, treatment and care. Read More
Adults ages 30-75.
Must have been invited to participate by a provider.