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JOURNEY Trial for Adults with Aortic Regurgitation
Protocol: STUDY00009231
Full Title
J-Valve to Treat Aortic Regurgitation via Transcatheter Therapy
Description
Aortic regurgitation (AR) is a heart valve problem that happens when the aortic valve doesn’t fully close. This allows blood to leak backward into the heart. When AR becomes severe, it can cause symptoms like shortness of breath, feeling tired, dizziness, chest pain, irregular heartbeat, and swollen ankles or feet. Over time, severe, symptomatic AR can lead to heart failure. Surgery is often needed to fix or replace the valve.

Researchers from the University at Buffalo (UB) are enrolling adults with AR in the JOURNEY trial. The goal of the study is to learn about the safety and performance of a new device called the J-Valve TF System. This device treats severe AR.

This study will last for 5 years. Participants will have the device implanted into their hearts. Then they will complete 7 follow-up visits for physical exams, blood tests, and to answer questions about their symptoms and health.

Participants can receive reimbursement for travel expenses for each visit.
Compensation: Yes
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Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Eligibility
Adults 18 years or older
Have been diagnosed with severe aortic regurgitation (AR)
Age Group: Adults
Principal Investigator: VIJAY IYER
ClinicalTrials.gov: Open Study
Contact(s)
DAWN HOLLER
dlh68@buffalo.edu
+1 716-829-6115
COURTNEY BISHOP
cabishop@buffalo.edu
+1 716-888-4859

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