Sjogren's Syndrome Blood Cell Study
Protocol: STUDY00004420
Full Title
Marginal Zone B Cells in Sjogren's Syndrome
Description
This study enrolls adults with Sjogren’s syndrome and healthy participants to for comparison. The purpose of this study is to whether a certain type of immune cell in the blood, called the marginal zone B cell, contributes to the problems in Sjogren’s syndrome.

This study involved one visit where you will give a blood sample. The blood will be given by standard blood drawing using a needle in the arm. The sample taken is about 45 mL, which is roughly 3 tablespoons of blood.

Technical Description

The study will examine the behavior of marginal zone B cells (MZB) in patients with Sjogren's syndrome compared to normal controls. We will examine metabolism of the MZB cells, production of cytokines by the MZBB cells and production of autoantibodies by the B cells.
Compensation: No
Eligibility
Adults ages 18+.
Must meet the criteria for Sjogren's syndrome
Sex and age matched normal controls (comparison group) will also be studied.
Age Group: Adults
Principal Investigator: JULIAN AMBRUS
Contact(s)
JULIAN AMBRUS
jambrus@buffalo.edu
+1 716-859-2985
Want to Learn More?
Enrollment Update

Due to COVID-19, new enrollment in research studies will be greatly limited. If you are interested in a study, there may be a longer waiting period to receive a response to your inquiry. View the guidance for research participants for additional information.

Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.