Infant retinopathy of prematurity Study
Protocol: SITE00000030
Full Title
Randomized, Controlled, Multi-Center Study To Assess The Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoaculation in Patients with Retinopathy of Prematurity
Description
This study enrolls newborn infants with treatable retinopathy of prematurity (ROP). ROP is is one of the leading causes of childhood blindness worldwide. The purpose of this study is to learn if aflibercept (Eyelea) works to treat this condition.

Infants in this study will be randomized (like the flip of a coin) to either take the study medication or to have the usual standard of care treatment for ROP, which is laser therapy. Your baby will be in this study for about 52 weeks after his/her birth. The study medication is given via an injection into the eye. The study will also involve blood draws, eye exams, and other physical exams for your baby. Study takes place at Oishei Children's Hospital.
Compensation: Yes
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Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Eligibility
Children (newborn infants).
Gestational age at birth must be 32 weeks or less, birth weight must be 1500g or less
Must have retinopathy of prematurity (ROP) that has not yet been treated.
Must weigh at least 800 g
Age Group: Children
Principal Investigator: Andrew Reynolds
Contact(s)
SHARON MICHALOVIC
sab1@buffalo.edu
+1 716-881-7975
Want to Learn More?

Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.

Your information will be shared only with the research study team for recruitment purposes and designated CTSI personnel for project quality assurance and will remain confidential. Your information will be stored indefinitely. Should you no longer want this information to be provided in the aforementioned ways, please contact ctsiresearch@buffalo.edu.