Study for Children with TBI Admitted to Oishei Children’s Hospital Intensive Care Unit
Protocol: STUDY00003009
Full Title
The use of Near-infrared Spectroscopy in Children with Severe Traumatic Brain Injury to Predict Adverse Events
This study enrolls children admitted to the intensive care unit with traumatic brain injury (TBI). The purpose of this study is to see if the forehead probe being studied can accurately monitor pressure and brain oxygen levels.

Your child will participate in this study for 48 hours. During that time, your child will have a non-invasive, painless probe placed on their forehead that will continuously monitor brain oxygen and blood volume levels. They will otherwise receive the same care as they usually would. This study takes place in the pediatric intensive care unit (PICU) at Oishei Children’s Hospital.

Compensation is not available.

Technical Description

This project will look at feasibility of using NIRS monitoring in children with TBI who have an ICP monitor at OCH.
The primary endpoint is to determine if NIRS can be used to predict increases in intracranial pressure or seizures before they occur.
The secondary endpoint is to determine what degree of changes in NIRS readings in cases of pediatric TBI with an ICP monitor, determines an increase in intracranial pressure.
Compensation: No
Children ages 0-18.
Have been admitted to the pediatric intensive care unit at Oishei Children’s Hospital with traumatic brain injury and an ICP monitor.
Age Group: Children
Principal Investigator: Ritesh Korumilli 
Ritesh Korumilli
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Enrollment Update

Due to COVID-19, new enrollment in research studies will be greatly limited. If you are interested in a study, there may be a longer waiting period to receive a response to your inquiry. View the guidance for research participants for additional information.

Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email and someone will assist you.