Kidney Paired Donation: A Randomized Trial to Increase Knowledge and Informed Decision-Making
This study gives education about kidney paired donation (KPD) for people who are interested in living kidney donation to a person they know. The purpose of this study is to learn the best way to educate people about kidney paired donation (KPD), sometimes called kidney exchanges.
During this study, you will answer questionnaires and you may watch a video about KPD. You will be in this study for about 3 months. Study visits take place at ECMC(Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215). Please contact firstname.lastname@example.org to learn more about this study.
Compensation is available.
Live donor kidney transplantation (LDKT) offers the most optimal survival and quality of life benefit for those with late-stage chronic kidney disease. In the United States, approximately 5,000 patients each year successfully find a compatible healthy living kidney donor (LKD) and undergo LDKT. However, one-third of potential LKDs who volunteer to undergo evaluation on behalf of an intended recipient are blood-type or cross-match incompatibility. Kidney paired donation (KPD) was developed as a strategy to provide these incompatible donor-recipient pairs with an innovative opportunity for LDKT, yet its uptake by potential donors and their intended LDKT recipients is not optimal. Fewer than half of eligible incompatible pairs agree to register in a KPD program when presented with this option. Guided by our own conceptual model, the objective of this application is to evaluate the effectiveness of a targeted intervention designed to increase knowledge of KPD risks and benefits, improve KPD self-efficacy, and reduce KPD concerns among potential LKDs and kidney transplant patients. Specifically, in a randomized controlled trial (RCT), 360 LKDs (n=180) and transplant patients (n=180) at three transplant centers will be randomly assigned to one of two KPD education conditions: (1) Usual Care (UC) or (2) UC plus video-based KPD education. Changes in KPD knowledge, self-efficacy, concerns, and informed decision-making will be assessed by questionnaire administration at baseline (pre-randomization), post-intervention (2 weeks), and follow up (3 months). Additionally, while not the target of intervention, we will gather follow-up data on KPD decision-making, participation, and reasons for non-participation at 3 months post-intervention. This research is innovative because it is the first to examine strategies for increasing knowledge of KPD risks and benefits, a critically important yet significant underutilized innovation in the field of kidney transplantation.
Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Adults ages 18+.
Speak English or Spanish.
Have completed the initial living donation health screening.
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the
contact information above or email email@example.com and someone will assist you.
Your information will be shared only with the research study team for recruitment purposes and designated CTSI personnel for project quality
assurance and will remain confidential. Your information will be stored indefinitely. Should you no longer want this information to be provided
in the aforementioned ways, please contact firstname.lastname@example.org.