Study of Patients with Traumatic Brain Injury in the Intensive Care Unit
Protocol: STUDY00003241
Full Title
Prospective analysis of early tracheostomy in severe traumatic brain injuries
Description
This study enrolls adults who have had a severe traumatic brain injury (TBI) who are in the Intensive Care Unit (ICU) at ECMC. The purpose of this study is to learn how the timing of giving patients with TBI a tracheostomy (putting a short tube directly into the trachea/windpipe through a small incision) can impact rates of ventilator associated pneumonia. Your participation in this study will involve receiving a tracheostomy as part of your usual care. If your doctors determine that you could benefit from a tracheostomy early in your care and you agree to the procedure, the tracheostomy will be performed. The study takes place at Erie County Medical Center. Compensation is not available for this study.

Technical Description

The purpose of this study is to evaluate whether implementation of a protocol designed to decrease the time to tracheostomy in severe traumatic brain injured (TBI) patients leads to a decrease in ventilator-associated pneumonia. We have previously demonstrated in a retrospective analysis that patients which receive early tracheostomy after experiencing a severe TBI appear to have lower incidences of ventilator-associated pneumonia. Moreover, we believe that early surgical tracheostomy placement decreases work of breathing leading to improved pulmonary toilet and airway dynamics. Overall, we feel that these benefits will ultimately lead to decreases in days of mechanical ventilation, ICU length of stay and potentially overall morbidity.
Compensation: No
Eligibility
Adults age 18+. Currently admitted to the Intensive Care Unit (ICU) at ECMC in Buffalo, NY. Diagnosed with traumatic brain injury (TBI) resulting from blunt or penetrating trauma. Requires endotracheal intubation to secure airway.
Age Group: Adults
Principal Investigator: JEFFREY JORDAN
Contact(s)
Judith Wilkins
jwilkins@ecmc.edu
+1 716-898-5066
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Enrollment Update

Due to COVID-19, new enrollment in research studies will be greatly limited. If you are interested in a study, there may be a longer waiting period to receive a response to your inquiry. View the guidance for research participants for additional information.

Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.