Participants 1-24 months old at Oishei Children's Hospital Emergency Deparment (ED) with suspected Bronchiolitis may be eligible for this study. Once enrolled, participants will undergo two carbon dioxide measurements, first will be done upon ED arrival at the Triage room, and the second one will be done upon ED discharge at patient's private room. Otherwise, participant will receive routine clinical care. Read More
Children ages 1-24 months old.
Have respiratory signs and symptoms and suspected bronchiolitis.
This study enrolls children and adults with skin conditions such as Atopic Dermatitis (eczema). The purpose of this study is to learn more about people who have been diagnosed with these conditions, including information about their health and the medications they take to manage their disease. Specifically, we want to understand how different treatments may affect the health of some patients differently than others. Read More
Adults or children.
Being prescribed medical therapy for atopic dermatitis.
We are doing this study to find out if there is a connection between poor sleep in children with cystic fibrosis and the development of diabetes. Cystic Fibrosis patient and the parent will complete a single 10 minute survey about how CF patient sleeps. The study team will collect some information about the child’s health including the results of an oral glucose tolerance test. Read More
Inclusion criteria include having cystic fibrosis, being 10 years old or older and either having an oral glucose tolerance test (a screen for CF-related diabetes) in 2020 or planning to have one in 2021. Exclusion criteria include a history of long-standing CF-related diabetes, liver failure or liver transplant or receipt of steroids within 6 weeks prior to the oral glucose tolerance test.
This study enrolls children and young adults with congenital anomalies of the kidney and urinary tract (CAKUT). The purpose of the study is to learn which gene mutation(s) may be responsible for this condition and to eventually find a gene therapy to treat this condition. Read More
Children and young adults ages 0-21 years old with CAKUT (congenital anomalies of the kidney and urinary tract) seen at Oshei Children's Hospital
Patient's family member without CAKUT.
This study enrolls children who are having an intracranial or spinal fusion procedure. The purpose of this study is to learn about the DNA of children who develop an infection after surgery. The results of this study may help us learn how to better control infections in children after surgery in the future. Read More
Children ages 5-15.
Are having an intracranial or spinal fusion procedure.
This study enrolls people with TRK fusion cancer. The purpose of this study is to learn more about the effectiveness of the drug VITRAKVI (generic name: larotrectinib) for TRK fusion cancer that has spread from the place where it started to other places in the body. TRK fusion cancer is a term used to describe a variety of common and rare cancers that are caused by a change to the NTRK (Neurotrophic Tyrosine Kinase) gene called a fusion. VITRAKVI is an approved drug that blocks the action of the NTRK gene fusion. Read More
Patients with TRK fusion cancer (locally advanced or metastatic solid tumor harboring an NTRK gene fusion).
Your physician has decided to treat you with larotrectinib.
This study enrolls children and young adults with Juvenile idiopathic arthritis. The purpose of this study is to understand the relationship between biochemical and genetic markers and the way a person's body responds to drugs. We also want to learn more about the development of lung disease in people with systemic juvenile idiopathic arthritis. Read More
-Children and young adults ages 1-21.
-Diagnosed with Juvenile idiopathic arthritis (sJIA) and has lung involvement.