This study explores reasons why siblings differ in weight status. It asks why do some siblings fall into different body weight groups (such as underweight versus overweight) even when they grow up in the same home environment? Read More

· Your children are same-sex siblings (both boys or both girls) between the ages of 11-16. · Your children differ in weight groups (i.e., underweight, overweight). · You live with both children. · You also fall into the overweight group. · Your family has no dietary restrictions. · Your children do not have depression, mood disorders, eating disorders, ADHD, or receive therapy for m...

This study is recruiting patients diagnosed with rapid-onset dystonia-parkinsonism (RDP). RDP is a rare movement disorder. It has symptoms of both dystonia (lasting muscle contractions) and Parkinson’s Disease (presence of tremor in one hand and a stiffness or slowing of movement). Patients may develop RDP suddenly or gradually over time. Read More

1) Patients with known/suspected RDP gene mutation OR those who have been identified as carriers/family members of someone with an RDP gene mutation 2)Patients who were previously enrolled in an earlier version of this study 3) 18 months of age or older 4) Access to Wi-Fi and a smart device (for example, a smartphone, laptop, tablet)

This study is for children ages 7 – 17 years old admitted to the Oishei Children’s Hospital emergency room (ER) who are experiencing nausea/vomiting. The goal of the study is to see if a different treatment (inhaled isopropyl alcohol) works better than the medication typically used (Zofran) for treating nausea/vomiting in pediatric patients. Read More

1. 7-17 years old

2. Chief complaint of nausea or vomiting

3. Weight >=15 kg (~33lbs)

4. BARF (nausea severity score) >=4/10

5. Admitted to the Oishei Children's Hospital emergency room

The goal of the UB Eating Among Teens Study (UB EATS) is to measure eating behaviors and neighborhood and household factors in 11 - 14-year-olds over the course of 3 years. Participation involves 7 visits to the UB Nutrition and Health Research Lab on South Campus over the 3-year period to answer questionnaires and eat snack foods. Low and middle-income families are encouraged to apply. Read More

-Adolescents ages 11 to 14

-Low to moderate income households

-No medical conditions or medications that impact appetite

-No allergies to study foods such as cookies, candy and potato chips

-Planning to live in the Western New York area for the next two years

-Willing to attend baseline and follow-up visits at a local research center

-Ad...

This study enrolls children and young adults with congenital anomalies of the kidney and urinary tract (CAKUT). The purpose of the study is to learn which gene mutation(s) may be responsible for this condition and to eventually find a gene therapy to treat this condition. Read More

Children and young adults ages 0-21 years old with CAKUT (congenital anomalies of the kidney and urinary tract) seen at Oshei Children's Hospital
Patient's family member without CAKUT.

This study enrolls children who are having orthodontic treatment and need a rapid maxillary expansion (RME) device. The purpose of this study is to learn about the effects of palatal expansion on jaw movement during sleep. Read More

-Children ages 7-14.
-Are under orthodontic care and need to use a rapid maxillary expansion (RME) device

This study enrolls high school students and teachers. The purpose of the study is to help students learn how to culture microbial organisms found in water samples from streams, rivers or lakes, and to teach about genome annotation, DNA sequencing and genomic DNA isolation. The study is also meant to help students learn more about scientific and health-related careers. Read More

-High School Biology (grades 9-12) teachers from Allegany, Cattaraugus, Chautauqua, Erie, Genesee, Livingston, Monroe, Niagara, Ontario, Orleans, Steuben, Wayne, Wyoming and Yates counties/schools. -Teachers must recruit their students; students cannot enroll in the study on their own.

This study enrolls children and adults who have tested positive for COVID-19. The purpose of this study is to collect and bank blood samples of people who have COVID-19. We will analyze these samples to understand more about the virus. Read More

Adults or children
Positive for SARS-CoV-2 or highly suspicious for SARS-CoV-2 (symptoms with known contact).

This study enrolls children who are admitted to the pediatric intensive care unit. The purpose of this study is to learn about the effects of blood transfusion on multiple organ dysfunction syndrome (MODS). Patient’s participation in this study will involve giving blood and urine samples and chest x-rays. During the study, we will store and analyze participant’s blood and urine to measure certain protein levels and collect information about their genetic material (DNA). Compensation is not available for this study. Read More

Children ages 1 month to 18 years who are admitted to the pediatric intensive care unit.
Critically ill pediatric patients receiving blood transfusion who have an expected length of stay after transfusion in the ICU of more than 24 hours (based on the best judgment of the attending ICU staff).

This study enrolls children and young adults who have Type 1 diabetes. Young adults with Type 1 diabetes experience stress related to their disease. The purpose of this study is to compare two different surveys for learning about stress related to having Type 1 diabetes. Read More

Children ages 13-17 and adults ages 18-19.
Diagnosis of Type 1 diabetes for more than 1 year.