This study enrolls children who are admitted to the pediatric intensive care unit. The purpose of this study is to learn about the effects of blood transfusion on multiple organ dysfunction syndrome (MODS). Patient’s participation in this study will involve giving blood and urine samples and chest x-rays. During the study, we will store and analyze participant’s blood and urine to measure certain protein levels and collect information about their genetic material (DNA). Compensation is not available for this study. Read More
Children ages 1 month to 18 years who are admitted to the pediatric intensive care unit.
Critically ill pediatric patients receiving blood transfusion who have an expected length of stay after transfusion in the ICU of more than 24 hours (based on the best judgment of the attending ICU staff).
We are looking for healthy children aged 4 to 5 (and their parent) to participate in a study to measure children’s reactions to different activities like playing games, eating snacks, and playing with a parent. Read More
Children ages 4-5.
Parent age at least 18.
-At least 1 parent who is considered overweight (by height/weight measurement).
-Parent and child fluent in English.
This study enrolls children and young adults who have Type 1 diabetes. Young adults with Type 1 diabetes experience stress related to their disease. The purpose of this study is to compare two different surveys for learning about stress related to having Type 1 diabetes. Read More
Children ages 13-17 and adults ages 18-19.
Diagnosis of Type 1 diabetes for more than 1 year.
This study enrolls adults and children ages 12+ who have obesity due to rare genetic disorders. The purpose of this study is to learn whether treatment with the study drug, setmelanotide, helps people with those disorders lose weight. Read More
Adults and children ages 12+.
Rare genetic disease patient with genetically confirmed diagnosis.
Obese (measured by BMI).
This study enrolls children ages 5-17 with asthma. The purpose of this research study is to find out if a breathing test called FeNO changes how doctors decide to treat your asthma. The FeNO test measures the amount of nitric oxide in the air you slowly breath out of your lungs and is a test for inflammation in the lungs. The FeNO test can also help doctors determine how well your asthma medications are suppressing inflammation in the lungs. Read More
Children ages 5-17.
Diagnosis of asthma.
Patients of the UBMD Pediatrics Allergy/Immunology clinic.
This study enrolls patients of UBMD Orthopedics and Sports Medicine who have recently had a concussion. The purpose of this study use eye tracking software to find out if eye movement is connected to recovery time from concussions. Our goal is to find better ways to diagnose concussions and understand how severe they are. Read More
-Adults and children ages 14-40.
-Physician had diagnosed a concussion within the past 10 days.
-Patient of UBMD Orthopedics and Sports Medicine clinic.
This study enrolls children ages 3-5 who attend certain Buffalo child care centers and their parents. This study is looking at early stressful experiences in the family and with friends at school. We are trying to find out how these experiences impact school readiness when children transition from preschool to kindergarten. We are also exploring how stressful experiences "get under the skin" and are measured in the stress hormone cortisol that we can measure in hair and saliva. Read More
Children ages 3-5.
Must be attending one of the participating child care centers in the larger Buffalo metro area.
This study enrolls children admitted to the intensive care unit with traumatic brain injury (TBI). The purpose of this study is to see if the forehead probe being studied can accurately monitor pressure and brain oxygen levels. Read More
Children ages 0-18.
Have been admitted to the pediatric intensive care unit at Oishei Children’s Hospital with traumatic brain injury and an ICP monitor.
This study enrolls people who are having dental surgery where some gum tissue is removed. The purpose of this study is to understand why there are differences between males and females in how severe gum disease is. Read More
Adults ages 18+
People having dental surgery at UB's School of Dental Medicine