Participants will be asked questions about a new cognitive processing test (how fast they can think). This study involves a single visit which takes about 20-minutes at the Conventus Medical Center in Buffalo. 50 multiple sclerosis patients and 50 healthy people will be enrolled. Read More

Physician established diagnosis of multiple sclerosis
18 years of age or older
Able to read and speak English
Not pregnant

This study enrolls men with prostate cancer. The purpose of this study is to compare using radium-223 and docetaxel chemotherapy treatment vs. using docetaxel alone in men with Metastatic Castration-Resistant Prostate Cancer (mCRPC). Radium223 has been FDA approved to treat men with prostate cancer that has spread to the bone, but it has not been approved for men with cancer that has spread to soft tissue or in combination with the chemotherapy drug docetaxel. Read More

Adults ages 18+.
Males with progressive Metastatic Prostate Cancer.
Have 2+ bone lesions.

This study enrolls adults diagnosed with head and neck cancer who have plans to complete chemoradiotherapy. The purpose of this study is to learn the best timing for feeding tube placement and speech therapy to create the best quality of life for patients. Read More

Adults ages 18+.
Patients with Head and Neck Cancer being treated at ECMC and Cancer Care WNY.
Patients planning to receive concurrent chemo-radiation therapy.

This study enrolls adults who have had a brain hemorrhage within the last 7 days. The purpose of the study is to learn whether it is better to keep taking or stop taking the medication statin after having a brain bleed. Read More

Adults ages 50+.
Have had bleeding in the brain (brain hemorrhage) within the last 7 days.
Were taking a statin drug.
People who may be eligible for this study will be contacted by study staff directly. Eligible participants will be inpatients of Buffalo General/Gates Vascular Institute.

This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR). The purpose of this study is to look at the safety and effectiveness of this new investigational device compared to the standard medical treatment. Read More

Adults ages 18+
Diagnosed with Tricuspid Regurgitation/Insufficiency

This study enrolls children and young adults with congenital anomalies of the kidney and urinary tract (CAKUT). The purpose of the study is to learn which gene mutation(s) may be responsible for this condition and to eventually find a gene therapy to treat this condition. Read More

Children and young adults ages 0-21 years old with CAKUT (congenital anomalies of the kidney and urinary tract) seen at Oshei Children's Hospital
Patient's family member without CAKUT.

This study enrolls adults who work in a pharmacy that is part of the Community Pharmacy Enhanced Services Network (CPESN). The purpose of this study is to learn about if it would be feasible to make a Community Heath Worker (CHW) program embedded within a pharmacy practice. Read More

Adults ages 18+.
Staff member in a pharmacy that is part of the Community Pharmacy Enhanced Services Network (CPESN) in New York and Missouri. Some of these pharmacies are implementing community health worker programs focused on patients with chronic health issues.
People eligible to participate in this study will be directly contacted by the study staff.

This study enrolls adults with esophageal cancer. The purpose of this study is to compare the effects of different combinations of medications to treat this cancer. Atezolizumab and tiragolumab are experimental drugs, which means the U.S. Food and Drug Administration (FDA) has not approved them, alone or in combination, for the treatment of esophageal cancer. Read More

Adults ages 18+.
Diagnosed with esophageal cancer (squamous cell carcinoma of the esophagus) in stage II-IIVA.
The cancer is unresectable, which means you are unable to unwilling to have surgery.
You have received chemoradiotherapy and your disease did not worsen.

This study enrolls adults who have had heart failure or heart attack or who are generally healthy. The purpose of this study is to learn more about how these types of cardiovascular issues happen at a biological level. We will do that by looking at the immune cells in the blood. Read More

Adults ages 18+
Generally healthy OR are presenting to the hospital with heart failure or acute myocardial infarction (heart attack).

This study enrolls children who are having orthodontic treatment and need a rapid maxillary expansion (RME) device. The purpose of this study is to learn about the effects of palatal expansion on jaw movement during sleep. Read More

-Children ages 7-14.
-Are under orthodontic care and need to use a rapid maxillary expansion (RME) device