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Nausea Treatment for Oishei Children's Hospital ER Patients
Protocol: STUDY00005944
Full Title
Inhaled Isopropyl Alcohol for the Treatment of Nausea/vomiting in a Pediatric Emergency Department-An open label, randomized clinical controlled trial
This study is for children ages 7 – 17 years old admitted to the Oishei Children’s Hospital emergency room (ER) who are experiencing nausea/vomiting. The goal of the study is to see if a different treatment (inhaled isopropyl alcohol) works better than the medication typically used (Zofran) for treating nausea/vomiting in pediatric patients.

Children will have equal chance to receive one of the three interventions to treat the nausea/vomiting symptoms: 1) inhaled isopropyl alcohol, 2) Zofran, or 3) inhaled placebo. The intervention will be chosen by chance, like flipping a coin. Those receiving the Zofran treatment will take a pill that melts in the mouth. Those receiving the inhaled isopropyl alcohol treatment will take deep breaths while an alcohol pad is held under the nose. Similarly, those receiving the inhaled placebo treatment will take deep breaths while a salt water pad is held under the nose.

All participants will be asked to rate their level of nausea before the treatment, at 10 minutes and 30 minutes after the treatment, and again before leaving the ER. Study participation will end once the child is discharged from the ER.
Compensation: No
1. 7-17 years old

2. Chief complaint of nausea or vomiting

3. Weight >=15 kg (~33lbs)

4. BARF (nausea severity score) >=4/10

5. Admitted to the Oishei Children's Hospital emergency room
Age Group: Both Adults and Children
Principal Investigator: Susana Ruano
Haiping Qiao
+1 716-323-0055
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