This study enrolls adults who work in a pharmacy that is part of the Community Pharmacy Enhanced Services Network (CPESN). The purpose of this study is to learn about if it would be feasible to make a Community Heath Worker (CHW) program embedded within a pharmacy practice. Read More

Adults ages 18+.
Staff member in a pharmacy that is part of the Community Pharmacy Enhanced Services Network (CPESN) in New York and Missouri. Some of these pharmacies are implementing community health worker programs focused on patients with chronic health issues.
People eligible to participate in this study will be directly contacted by the study staff.

This study enrolls adults with esophageal cancer. The purpose of this study is to compare the effects of different combinations of medications to treat this cancer. Atezolizumab and tiragolumab are experimental drugs, which means the U.S. Food and Drug Administration (FDA) has not approved them, alone or in combination, for the treatment of esophageal cancer. Read More

Adults ages 18+.
Diagnosed with esophageal cancer (squamous cell carcinoma of the esophagus) in stage II-IIVA.
The cancer is unresectable, which means you are unable to unwilling to have surgery.
You have received chemoradiotherapy and your disease did not worsen.

This study enrolls adults who have had heart failure or heart attack or who are generally healthy. The purpose of this study is to learn more about how these types of cardiovascular issues happen at a biological level. We will do that by looking at the immune cells in the blood. Read More

Adults ages 18+
Generally healthy OR are presenting to the hospital with heart failure or acute myocardial infarction (heart attack).

This study enrolls children who are having orthodontic treatment and need a rapid maxillary expansion (RME) device. The purpose of this study is to learn about the effects of palatal expansion on jaw movement during sleep. Read More

-Children ages 7-14.
-Are under orthodontic care and need to use a rapid maxillary expansion (RME) device

This study enrolls women ages 18-39 who exercise regularly. The purpose of this study is to learn about the relationship between vitamin D and recovery of skeletal muscle damage in females. Read More

Women ages 18-39.
Exercise regularly.

This study enrolls people who have mitral regurgitation (MR). Mitral regurgitation happens when the heart’s mitral valve does not close tightly. The purpose of this trial is to evaluate a new investigational device called the Tendyne™ Mitral Valve System. The Tendyne Mitral Valve System is designed for the treatment of a diseased, damaged or malfunctioning mitral valve. This trial will collect information on how safe and effective this device is to treat a leaking mitral valve compared to the commercially available MitraClip® System. Read More

-Adults ages 18+.
-Have symptomatic, moderate-to-severe/severe mitral regurgitation (MR) or severe mitral annular calcification (MAC)
-Your medical providers have decided a transcatheter therapy is more appropriate than open surgery.

This study enrolls people who need tube shunt implantation for the treatment of their severe glaucoma. The purpose of this study is to learn which type of tube shunt (a device used during the surgery) works the best. Read More

Adults ages 18+.
Have significant uncontrolled glaucoma despite medical, laser or previous surgery that requires tube shunt implantation.
Are scheduled for glaucoma tube shunt implantation surgery.

This study enrolls high school students and teachers. The purpose of the study is to help students learn how to culture microbial organisms found in water samples from streams, rivers or lakes, and to teach about genome annotation, DNA sequencing and genomic DNA isolation. The study is also meant to help students learn more about scientific and health-related careers. Read More

-High School Biology (grades 9-12) teachers from Allegany, Cattaraugus, Chautauqua, Erie, Genesee, Livingston, Monroe, Niagara, Ontario, Orleans, Steuben, Wayne, Wyoming and Yates counties/schools. -Teachers must recruit their students; students cannot enroll in the study on their own.

This study enrolls people who are HIV positive who are taking certain medication. If a person take Stribilid® or Genvoya®, there may be changes in the way their body uses or removes other medications. We want to study another approved treatment, Biktarvy®, that we believe is less likely to affect how the body handles other medications that a person is currently taking. This switch may improve quality of life. Read More

-Adults ages 18+.
-Positive for HIV.
-Taking current antiretroviral therapy GenvoyaTM or StribildTM for HIV-1 infection.
-Taking at least 1 or more other prescription medications.

This study is looking for women ages 18-24 who are in college. The purpose of this study is to get feedback about program designed for friends to help protect one another against sexual assault. Read More

Adult women ages 18-24.
Enrolled in a 4 year college or university