This study is recruiting volunteers for a dental study through the University at Buffalo (UB) Microbiome Center in the UB School of Dental Medicine. The study team is researching if they can make accurate copies of bacteria patterns in mouth plaque (the “stuff” that collects between gums and teeth). The results of the study will help dentists to better understand how gum disease develops and comes back over time. Read More
1. At least 21 years old
2. Have at least sixteen (16) teeth
3. Not currently pregnant
4. Not currently wearing braces or orthodontic appliances
Study will assess adult participants for gum disease and bacteria in the mouth. The dental exams are the same exams that normally take place in dentist’s office. Saliva and plaque will be collected from participants. Visits will be every 2 weeks or every month. Study lasts 10-12 months. Read More
At least 25 years old
At least sixteen (16) teeth
To be determined at Screening Visit: Presence of at least 4 sites (anterior or posterior) with probing pocket depths (PD) > 5 mm and < 6 mm and concomitant clinical attachment loss.
To be determined by testing subgingival plaque after the Screening Visit: Have detectable Pg in subgingival plaque as assessed by PCR (we will take sampl...
This study enrolls children who are having orthodontic treatment and need a rapid maxillary expansion (RME) device. The purpose of this study is to learn about the effects of palatal expansion on jaw movement during sleep. Read More
-Children ages 7-14.
-Are under orthodontic care and need to use a rapid maxillary expansion (RME) device
We are looking for healthy adults age 21+ for a research study. The purpose of this study is to learn more about how bacteria in the mouth work. We hope that with this understanding, new treatments can be designed to prevent disease. Read More
In general good health.
Pregnant women may not participate.