This study is recruiting volunteers for a dental study through the University at Buffalo (UB) Microbiome Center in the UB School of Dental Medicine. The study team is researching if they can make accurate copies of bacteria patterns in mouth plaque (the “stuff” that collects between gums and teeth). The results of the study will help dentists to better understand how gum disease develops and comes back over time. Read More
1. At least 21 years old
2. Have at least sixteen (16) teeth
3. Not currently pregnant
4. Not currently wearing braces or orthodontic appliances
Patients who use cannabis on a regular basis may be at a greater risk for sedation-related complications. In our dental sedation suite, we routinely sedate patients for oral surgery three days per week. We have recently noted an increase in patients who use cannabis regularly. This study will gather self-reported cannabis use history via a questionnaire, and analyze sedation records to assess cannabis use's effect on sedation. Read More
-18 or greater years of age and report to our oral surgery clinic for treatment.
-Able to consent to their own medical treatment.
-Willing to sign informed consent and complete the questionnaire.
-Able to comprehend the content of the questionnaire and consent form in English.
Study will assess adult participants for gum disease and bacteria in the mouth. The dental exams are the same exams that normally take place in dentist’s office. Saliva and plaque will be collected from participants. Visits will be every 2 weeks or every month. Study lasts 10-12 months. Read More
At least 25 years old
At least sixteen (16) teeth
To be determined at Screening Visit: Presence of at least 4 sites (anterior or posterior) with probing pocket depths (PD) > 5 mm and < 6 mm and concomitant clinical attachment loss.
To be determined by testing subgingival plaque after the Screening Visit: Have detectable Pg in subgingival plaque as assessed by PCR (we will take sampl...
This study enrolls children who are having orthodontic treatment and need a rapid maxillary expansion (RME) device. The purpose of this study is to learn about the effects of palatal expansion on jaw movement during sleep. Read More
-Children ages 7-14.
-Are under orthodontic care and need to use a rapid maxillary expansion (RME) device
This study enrolls people who are scheduled for a surgery at ECMC involving removing the tissue that makes saliva. The purpose of this study is to use tissue samples that otherwise would have been discarded to learn more about how salivary gland inflammation happens at a molecular level. We hope this will lead to new ways to diagnose and treat salivary gland inflammatory diseases. Read More
Adults ages 18+
Scheduled for a surgery at ECMC involving salivary gland excision (e.g. Neck Dissection Surgery, etc.)
Any sample of salivary gland tissue that would otherwise be discarded will be included for the study.
This study enrolls adults who are having a head or neck surgery that will remove tissue that makes saliva. This research is being done to gain a better understanding of the tissue that makes saliva (salivary gland tissue). Read More
-Adults ages 18+
-Come to the ECMC Department of Head and Neck Surgery for a procedure involving removal of salivary tissue.
This study enrolls people who are having dental surgery where some gum tissue is removed. The purpose of this study is to understand why there are differences between males and females in how severe gum disease is. Read More
Adults ages 18+
People having dental surgery at UB's School of Dental Medicine