Evasion of destruction and survival of Oral Microbiota within Macrophage and Dendritic Cells.
Protocol: 030-626714
Full Title
Evasion of destruction and survival of Oral Microbiota within Macrophage and Dendritic Cells.
Description
We are looking for healthy adults age 21+  for a research study. The purpose of this study is to learn more about how bacteria in the mouth work.  We hope that with this understanding, new treatments can be designed to prevent disease.

You will be in this research study for as many visits as you are willing to come in for.  The visits take about 20-30 minutes and you will give a blood sample during the visit. Visits take place at UB's South Campus.

Compensation is not available for this study.

Technical Description

Macrophages and dendritic cells are key innate immune cells involved in the response to infection. Crucial responses include migration to the site of infection and eradication of microorganisms by phagocytosis and killing with both reactive oxygen species generation and enzyme dependent mechanisms, as well as presentation of antigens to the adaptive immune system. This project focuses on how intact oral microorganisms are able to modulate cellular activation and phagocytic maturation processes to impair the normal protective response of macrophages and dendritic cells.
Compensation: No
Eligibility
Age 21+.
In general good health.
Pregnant women may not participate.
Age Group: Adults
Principal Investigator: JASON KAY
Contact(s)
JASON KAY
jasonkay@buffalo.edu
+1 716-829-2844
Want to Learn More?
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.