Inter-species and host-derived cues that modulate colonization of Porphyromonas gingivalis
The University at Buffalo (UB) School of Dental Medicine is looking for volunteers to join a gum disease study. The study aims to learn more about how harmful bacteria grow in the mouth and cause periodontal (gum) disease. We are interested in Porphyromonas gingivalis (P. ginivalis), a pathogen involved in gum disease.
All study visits occur on the UB South Campus at Squire Hall, School of Dental Medicine (at Main Street and Bailey Avenue). To determine study eligibility, volunteers attend a screening visit where a licensed dental clinician will complete a full dental exam to look for gum disease. Dental plaque (the sticky stuff between your teeth and gums) is tested for P. gingivalis. This visit takes about 1 – 1.5 hours.
Enrolled study participants will then attend a baseline visit for sample collection. This visit takes about 2 hours. Subjects with P. gingivalis will attend 9 additional monthly visits for dental exams and spit/plaque collection. Participants can earn $50 for completing each study visit. You will also have the option to come in every 2 weeks, versus monthly. These additional visits provide more data and you will receive an extra $50 for each added visi
This prospective longitudinal observational study will identify microbial species that serve as putative modulators of Porphyromonas gingivalis (Pg) colonization through analysis of time-series metagenomic data via dynamical systems models. The study will also evaluate the role of the microbiome functional capabilities and heme availability on Pg levels.
Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Adults aged 25 years or older
Have at least 16 natural teeth
Have the bacterium Porphyromonas gingivitis in their mouth
Have gum disease (which will be determined by study staff)
Do not wear braces or other orthodontic equipment
Have not had periodontal treatment or surgery in the past year
Not currently pregnant
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the
contact information above or email email@example.com and someone will assist you.
Your information will be shared only with the research study team for recruitment purposes and designated CTSI personnel for project quality
assurance and will remain confidential. Your information will be stored indefinitely. Should you no longer want this information to be provided
in the aforementioned ways, please contact firstname.lastname@example.org.