The purpose of this study is to learn more about the advantages and disadvantages of two brief quitting smoking approaches that could be cost-effective in assisting individuals who suffer from serious mental illness. The first approach is brief advice combined with the use of nicotine gum and patches. The second approach uses an app on your smartphone combined with the use of nicotine gum and patches. Read More

Inclusion Criteria
(1) Current DSM-5 diagnosis of schizophrenia, schizoaffective, bipolar, or recurring major depressive disorder;
(2) Functional impairment as indicated by a score of_2 or greater on the WHODAS 8 item version
(3) Smoker as indicated by smoking  5 cigarettes per day over the past 6 months;
(4) Desire to quit smoking as indicated by self-reported serious...

Study to evaluate reducing worry, anxiety, and stress in underserved communities highly impacted by the COVID-19 pandemic. Mindfulness Based Stress Reduction programs (meditation, breathing and movement) will be delivered via video / teleconference or a smart phone APP. The study lasts approximately 21 weeks. Read More

Inclusion:
(1) age 18 years and older
(2) a baseline score ≥26 (clinically significant worry) on the Penn State Worry Questionnaire-Abbreviated
(3) fluency in English
(4) reside in one of the underserved, census-identified primarily African American communities in Buffalo, NY
Exclusion:
(5) severe depression
(6) active suicidal intent
(7) DSM-V diagno...

This study enrolls adults at risk for Type 2 Diabetes who are interested in weight loss. The purpose of this study is to learn the impact of a behavioral weight-loss treatment. Read More

Adults ages 18+
Have prediabetes (Blood A1c at or near prediabetic range of 5.4%-6.7%).
Not diagnosed with Type 2 diabetes or substance abuse/dependence.

This study is looking for women ages 18-24 who are in college. The purpose of this study is to get feedback about program designed for friends to help protect one another against sexual assault. Read More

Adult women ages 18-24.
Enrolled in a 4 year college or university

This study enrolls adults with bipolar disorder that is currently not well controlled who will be starting treatment. The purpose of the research is to learn about the relationship between changes in the amount of calcium in platelets and mood change in people with bipolar disorder. Read More

Adults ages 18-75
Healthy, diagnosed with bipolar disorder (mania, bipolar depression, or mixed state)
Acutely ill and initiating a new standard of care treatment for their bipolar disorde

This study enrolls healthy adults. The purpose of this study is to learn how people use memories and make decisions about their behavior. Read More

Healthy adults ages 18-64.
English spoken as first language.
USA residents.
Cannot be pregnant.

This study enrolls children ages 3-5 who attend certain Buffalo child care centers and their parents. This study is looking at early stressful experiences in the family and with friends at school. We are trying to find out how these experiences impact school readiness when children transition from preschool to kindergarten. We are also exploring how stressful experiences "get under the skin" and are measured in the stress hormone cortisol that we can measure in hair and saliva. Read More

Children ages 3-5.
Must be attending one of the participating child care centers in the larger Buffalo metro area.

The purpose of the study is to help understand the relationship between eating behavior and the growth and development of overweight and obesity in children. Read More

-Children ages 8-11
- At risk for obesity

We are looking for adults with schizophrenia for a research study. This study is being done to see if the study drug may improve the ability to remember, think clearly and/or solve problems in people with schizophrenia. Read More

Adults ages 18-50.
Must have been diagnosed with schizophrenia for at least 2 years.