This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR) and have Heart Failure symptoms which are not under control despite treatment with current available therapies. The purpose of this study is to compare a new investigational (experimental) device plus optimal drug therapy with optimal drug therapy alone. Read More
Adults ages 18+
Diagnosed with moderate or greater Tricuspid Regurgitation/Insufficiency with Heart Failure symptoms
This study enrolls people with atrial fibrillation (AF) who have had a recent brain bleed (with in 4 months). The purpose of this study is to compare the effects of apixaban (also known as Eliquis®) with aspirin in patients to see which is better in preventing strokes and death. Read More
-Adults ages 18+.
-Diagnosed with Intracerebral hemorrhage (ICH).
-Have non-valvular atrial fibrillation or atrial flutter.
This study enrolls adults who have have a patent foramen ovale (PFO) and have had a stroke. The purpose of this study is to look at closing the PFO to reduce your risk for another stroke using a market-approved medical device called a septal occluder. Read More
Adults ages 18-70.
Patient has been evaluated by a neurologist and diagnosed with an ischemic stroke presumed to be an embolic stroke of undetermined source (ESUS) within the last 365 days prior to enrollment.
Patient has presence of a patent foramen ovale (PFO).
This study enrolls people ages 18-80 whose doctor has told them that they have had a myocardial infarction (“heart attack”). This study looks at the use of a temporary circulatory assist device before the catherization procedure to support your heart with pumping blood. This device is called the Impella CP® (“Study Device”). Read More
-Adults ages 18-80.
-First myocardial infarction.
-Patient presents to the hospital between 1 - 5 hours of chest pain onset.
This study enrolls adults who have had a recent stroke or stroke symptoms. The purpose of this study is to compare how well the study drug (tenecteplase) works for people with stroke symptoms. Read More
-Adults ages 18+.
-Have been diagnosed with a stroke or stroke symptoms.
-Please contact the research team for other eligibility criteria.
This study enrolls adults ages 20+ who are having a procedure for AFib. The purpose of this study is collect information to better understand the short and long term outcomes of the devices being used to treat arrhythmia. Read More
Adults ages 20+.
Diagnosed with recurrent symptomatic Paroxysmal Atrial Fibrillation (AFib).
Having an ablation procedure to treat AFib.
This study enrolls people who have had a stroke in the past 2 weeks. This research is being done to figure out whether treatment for sleep apnea in people who have had a stroke or transient ischemic attack (TIA or "mini stroke"), improves recovery from stroke and helps prevent future stroke, heart problems, and death. Read More
Adults ages 18+.
Are at an inpatient at an enrolling site (Buffalo General Hospital or Gates Vascular Institute).
Have had an ischemic stroke or TIA within the past 14 days.
Use a CPAP machine.
This study enrolls adults who are hospitalized for acute ischemic stroke. The purpose of this study is to learn how safe and effective the pRESET Thrombectomy Device is for the treatment of this condition and for removing the blood clot. Read More
Adults ages 18+.
Currently admitted to the hospital for an acute ischemic stroke that began in the last 8 hours.
This study enrolls people who have been diagnosed with a subarachnoid hemorrhage (SAH), a type of brain bleed. The most common complication after SAH is blood vessel narrowing (vasospasm) in the brain. The purpose of this study is to find out if an investigational (experimental) device, which has not yet been approved by the FDA, is safe and can help treat patients who develop vasospasm after treatment of a SAH. Read More
People ages 18+
Developed vasospasm complications after treatment for SAH
This study enrolls people who are in the Emergency Department. The purpose of this study is to test a device (made by the study sponsor, Forest Devices) that may be able to tell if someone is having a stroke. This device is portable, so it might someday be used on an ambulance to give caregivers early information on whether a patient who seems to be having a stroke is actually having a stroke or not. The device is painless and uses electrodes to gather information about brain activity. Read More
Adults ages 18+ who have been brought to a participating Emergency Department with the signs of a stroke.