This is a study to evaluate the efficacy of Chemo Mouthpiece® in minimizing patient-reported symptoms associated with oral mucositis in cancer patients receiving chemotherapy. The Chemo Mouthpiece(R) is a novel device to make it easier to deliver cryotherapy (ice chips). Read More

Aged 18-80 years
Planned to receive at least 2 cycles of infused stomatotoxic chemotherapy regimens
Be willing and able to complete all study-related activities

This study enrolls men with prostate cancer. The purpose of this study is to compare using radium-223 and docetaxel chemotherapy treatment vs. using docetaxel alone in men with Metastatic Castration-Resistant Prostate Cancer (mCRPC). Radium223 has been FDA approved to treat men with prostate cancer that has spread to the bone, but it has not been approved for men with cancer that has spread to soft tissue or in combination with the chemotherapy drug docetaxel. Read More

Adults ages 18+.
Males with progressive Metastatic Prostate Cancer.
Have 2+ bone lesions.

This study enrolls adults diagnosed with head and neck cancer who have plans to complete chemoradiotherapy. The purpose of this study is to learn the best timing for feeding tube placement and speech therapy to create the best quality of life for patients. Read More

Adults ages 18+.
Patients with Head and Neck Cancer being treated at ECMC and Cancer Care WNY.
Patients planning to receive concurrent chemo-radiation therapy.

This study enrolls adults with esophageal cancer. The purpose of this study is to compare the effects of different combinations of medications to treat this cancer. Atezolizumab and tiragolumab are experimental drugs, which means the U.S. Food and Drug Administration (FDA) has not approved them, alone or in combination, for the treatment of esophageal cancer. Read More

Adults ages 18+.
Diagnosed with esophageal cancer (squamous cell carcinoma of the esophagus) in stage II-IIVA.
The cancer is unresectable, which means you are unable to unwilling to have surgery.
You have received chemoradiotherapy and your disease did not worsen.

This study enrolls people who have been diagnosed with head and neck cancer and are being treated with neck radiation therapy. The purpose of this study is to find out the number of people who develop narrowing of their carotid arteries (Carotid Artery Stenosis) due to neck radiation and understand how tobacco use and diabetes effect the worsening of carotid artery stenosis. Read More

Adults age 18+
Diagnosis of neck cancer and undergoing one-sided neck radiation
Must have no history of stroke

This study enrolls adults with head and neck cancer. The purpose of the study is to learn if a light device used in the mouth during chemotherapy and radiation can help prevent oral mucositis. Read More

Diagnosed with cancer (pathologically confirmed squamous cell carcinoma) of the oral cavity, oropharynx, tonsil or base of tongue.
Scheduled to have a continuous course of Intensity-Modulated Radiation Therapy (IMRT) over an estimated 6 to 8 weeks.