Search and volunteer to participate in these available studies at UB. Your participation in research doesn't just benefit you, it helps advance healthcare for our entire community.
People diagnosed with chronic heart failure may be eligible for a new clinical trial. The goal of this study is to see if a new device (the APTURE system) can help to improve symptoms related to heart failure. Read More
Eligibility:
-Adults 18 years or older
-Have been diagnosed with heart failure
-Speak English
The University at Buffalo (UB) Department of Neurosurgery is conducting a study for patients of Gates Vascular Institute (GVI) that have had a stroke. The goal of the study is to test the effectiveness of a new magnetic resonance imaging (MRI) device for stroke patients. Read More
Eligibility:
Adults 18 years or older who have had a stroke and are patients at Gates Vascular Institute
The University at Buffalo's Neurology Department is working on a study funded by the National Institute of Health. This study is for adults who have had a stroke because their brain's blood vessels were severely narrowed. It's a special type of study where neither the participants nor the researchers know who gets which treatment, which is decided randomly, like tossing a coin. The aim is to see if using different medications together can help prevent blood clots, and this will be combined with medicine and advice on how to live healthier. Read More
Eligibility:
Adults at least 30 years of age
Had a stroke within the last 30 days
The University at Buffalo (UB) School of Pharmacy and Pharmaceutical Sciences is enrolling adults currently admitted to the Buffalo General Medical Center and being treated by the cardiology team for a 3-month study. The goal of the study is to see if better communication between a hospital pharmacist and a patient’s primary care physician is helpful after being released from the hospital. Read More
Eligibility:
Adults 18 years or older
Admitted to Buffalo General Medical Center and are being treated by the cardiology team
The University at Buffalo (UB) Department of Medicine is enrolling adults with atrial fibrillation (or “AFib”) that are worried about their risk of having a stroke. People with AFib have a heart condition that causes the upper chambers of their hearts to beat irregularly, or differently than they should. The goal of the study is to see if a new study device (the CLAAS System) can reduce the risk of stroke without the need for blood thinners. Read More
Eligibility:
Adults 18 years or older
Have been diagnosed with atrial fibrillation (or AFib)
Are at risk for stroke
The University at Buffalo (UB) Department of Medicine is enrolling adults with complex heart disease in a clinical trial. The goal of the study is to see if a new heart pump (the Impella ECP) can help the heart during surgery. Read More
Eligibility:
Adults 18 years or older
Have complex heart disease
Need to have heart surgery to help treat their heart disease
The University at Buffalo (UB) Department of Surgery is looking for adults that have been diagnosed with peripheral arterial disease (or when plaque builds up on artery walls and makes it more difficult for blood to flow) for a study. The goal of the study is to see if there are differences between two devices (the VBX Device and the Bare Metal Stent) in helping to treat peripheral arterial disease. Read More
Eligibility:
Adults over the age of 18 years old
Have peripheral arterial disease
Are scheduled for iliac artery surgery
This clinical trial is exploring the use of an investigational drug (sGC stimulator vericiguat/MK-1242) in patients with chronic heart failure. Specifically, trial doctors are interested in assessing the safety of this drug and if it works well to lower some of the risks of heart failure. All participants will be able to stay on their current heart failure medication during the 2-year trial period. Read More
Eligibility:
1) History of chronic stable, NYHA class II to IV CHF
2) NT-proBNP 600 - 6000
3) LVEF of <40% assessed within 12 months before randomization
Study to assess the effect of dapagliflozin as compared with placebo in patients with heart failure who have been stabilized during hospitalization for acute heart failure. Patients will be followed for a maximum of 2 months. Read More
Eligibility:
1. Currently hospitalized with AHF with symptoms of AHF.
2. LVEF <40% within the past 12 months
3. Elevated NT-proBNP, >1600 pg/ml
4. > 18 years of age
5. eGFR >30