Search and volunteer to participate in these available studies at UB. Your participation in research doesn't just benefit you, it helps advance healthcare for our entire community.

Highlighted Searches
Search Clinical Trials
Filter on any fields below
?
Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Showing 1 - 10 of 40 Clinical Trials
Description:
This study is for participants diagnosed with complex heart disease and reduce left heart function and involves a heart procedure called a Percutaneous Coronary Intervention (PCI). Participants may be eligible for this study if their doctor has determined that an Impella® device could be beneficial during the PCI procedure. The goal of this study is to assess if using the Impella® device during high-risk PCI procedures will result in an improvement in symptoms, heart function and health after the heart procedure compared to the current standard of care. Read More
Eligibility:
1. Between the ages of 18 - 90 years old 2. Clinical presentation and baseline left ventricular function are as follows (either 2A or 2B must be present): 2A. Subject has CCS or NSTEMI with an LVEF ≤40% OR 2B. Subject has STEMI ≥24 hours and <30 days after symptom onset with an LVEF ≤30% 3. Local heart team (interventional cardiologist and cardiac surgeon) has determine...
Contact(s)
DAWN HOLLER
dlh68@buffalo.edu
+1 716-829-6115
Description:
This study is enrolling patients diagnosed with a pulmonary embolism (PE), or a blood clot trapped in the lung. The goal of the study is to compare two treatments for PE: (1) the FlowTriever Retrieval/Aspiration System (referred to as “FlowTriever”) which removes the clot by pulling it into a catheter (a flexible plastic tube) and (2) using catheter directed thrombolysis (“CDT”) devices which are placed close to the PE and slowly release a medication to dissolve the clot. Read More
Eligibility:
1. Age 18 years or older 2. Echo, compute tomographic pulmonary angiography (CTPA), or pulmonary angiographic evidence of any proximal filing defect in at least one main or lobar pulmonary artery. 3. Classification of intermediate-high-risk PE by ESC Guidlines 2019, including ALL of the following: a. Clinical signs and symptoms consistent with acute PE, or PESI class III-V, or sPESI >/=1...
Contact(s)
DAWN HOLLER
dlh68@buffalo.edu
+1 716-829-6115
Description:
This clinical trial is exploring the use of an investigational drug (sGC stimulator vericiguat/MK-1242) in patients with chronic heart failure. Specifically, trial doctors are interested in assessing the safety of this drug and if it works well to lower some of the risks of heart failure. All participants will be able to stay on their current heart failure medication during the 2-year trial period. Read More
Eligibility:
1) History of chronic stable, NYHA class II to IV CHF 2) NT-proBNP 600 - 6000 3) LVEF of <40% assessed within 12 months before randomization
Contact(s)
KELLEY CAROZZOLO (Bilson)
kjc28@buffalo.edu
+1 716-898-5653
Description:
Study to assess the effect of dapagliflozin as compared with placebo in patients with heart failure who have been stabilized during hospitalization for acute heart failure. Patients will be followed for a maximum of 2 months. Read More
Eligibility:
1. Currently hospitalized with AHF with symptoms of AHF.
2. LVEF <40% within the past 12 months
3. Elevated NT-proBNP, >1600 pg/ml
4. > 18 years of age
5. eGFR >30
Contact(s)
KELLEY CAROZZOLO (Bilson)
kjc28@buffalo.edu
+1 716-898-5653
Description:
Eligibility:
-Adults ages 18-80
-Has a single unruptured target intracranial aneurysm (IA) located on the internal carotid artery (ICA) or its branches.
Contact(s)
JENNIFER GAY
jgay@ubns.com
+1 716-888-4811
Description:
An early feasibility study to evaluate the safety and efficacy of Delphi Revascularization device for clot retrieval. This is for hospital patients with Anterior circulation ischemic stroke. Up to 8hrs of symptom onset or last known well time. Read More
Eligibility:
At least 18 years of age at time of consent;
The patient or patient’s LAR has signed and dated an ICD using the Institutional Review Board (IRB) and Medtronic Approved ICD and agrees to comply with protocol requirements. Health Insurance Portability and Accountability Act of 1996 (HIPAA) authorization has been provided and signed by the patient or patient’s LAR
Has baseline N...
Contact(s)
JENNIFER GAY
jgay@ubns.com
+1 716-888-4811
Description:
This study enrolls adults with a blockage in an artery in their heart that needs to be tested to determine if it should be treated. The purpose of this study is to collect data and measurements to find out if you need you need an interventional procedure to open your blood vessel or artery. Read More
Eligibility:
Adults ages 18+.
Have at least 1 non-stented lesion in 1 or more major epicardial vessels of 40-90% angiographic stenosis.
Contact(s)
ROBIN STEIN
rmstein3@buffalo.edu
+1 716-888-4859
Description:
This study enrolls people who have been diagnosed with a blood clot blocking an artery in their brain (stroke). The blocked artery is opened by removing the blood clot using a small catheter (thin tube) device that is inserted into an artery through your arm or leg that leads to your brain. The purpose of this study is to find out if this specific new investigational catheter (ZOOM) leads to improved outcomes at 90 days. Read More
Eligibility:
Adults ages 18+
Diagnosed with a stroke
Nonpregnant females
Contact(s)
JENNIFER GAY
jgay@ubns.com
+1 716-888-4811
Description:
This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR). The purpose of this study is to look at the safety and effectiveness of this new investigational device compared to the standard medical treatment. Read More
Eligibility:
Adults ages 18+
Diagnosed with Tricuspid Regurgitation/Insufficiency
Contact(s)
COURTNEY BISHOP
cabishop@buffalo.edu
Description:
This study enrolls older adults who may have a completely or partially blocked blood vessel(s) in their heart causing a type of heart attack known as a ST-elevation myocardial infarction (STEMI). This may need a medical procedure called “Percutaneous Coronary Intervention (PCI)” to open narrowed or blocked blood vessel(s). This is sometimes called an angioplasty or ‘balloon procedure’ often with stent placement at the same time. The purpose of this study is to learn about the safety and benefits of different types of treatment for this condition. Read More
Eligibility:
Adults ages 60+.
You have had a significant ST-elevation myocardial infarction or left bundle branch block (LBBB).
Your physician plans to perform trans-radial Percutaneous Coronary Intervention (PCI).
Contact(s)
DAWN HOLLER
dlh68@buffalo.edu
+1 716-829-6115
Showing 1 - 10 of 40 Clinical Trials
Not finding what you are looking for? Add your profile to the Buffalo Research Registry or ResearchMatch to be matched with future studies.