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Search and volunteer to participate in these available studies at UB. Your participation in research doesn't just benefit you, it helps advance healthcare for our entire community.

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Showing Active Clinical Trials
Description:
This clinical trial is exploring the use of an investigational drug (sGC stimulator vericiguat/MK-1242) in patients with chronic heart failure. Specifically, trial doctors are interested in assessing the safety of this drug and if it works well to lower some of the risks of heart failure. All participants will be able to stay on their current heart failure medication during the 2-year trial period. Read More
Eligibility:
1) History of chronic stable, NYHA class II to IV CHF 2) NT-proBNP 600 - 6000 3) LVEF of <40% assessed within 12 months before randomization
Contact(s)
KELLEY CAROZZOLO (Bilson)
kjc28@buffalo.edu
+1 716-898-5653
Description:
Study to assess the effect of dapagliflozin as compared with placebo in patients with heart failure who have been stabilized during hospitalization for acute heart failure. Patients will be followed for a maximum of 2 months. Read More
Eligibility:
1. Currently hospitalized with AHF with symptoms of AHF.
2. LVEF <40% within the past 12 months
3. Elevated NT-proBNP, >1600 pg/ml
4. > 18 years of age
5. eGFR >30
Contact(s)
KELLEY CAROZZOLO (Bilson)
kjc28@buffalo.edu
+1 716-898-5653
Description:
Eligibility:
-Adults ages 18-80
-Has a single unruptured target intracranial aneurysm (IA) located on the internal carotid artery (ICA) or its branches.
Contact(s)
JENNIFER GAY
jgay@ubns.com
+1 716-888-4811
Description:
This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR). The purpose of this study is to look at the safety and effectiveness of this new investigational device compared to the standard medical treatment. Read More
Eligibility:
Adults ages 18+
Diagnosed with Tricuspid Regurgitation/Insufficiency
Contact(s)
COURTNEY BISHOP
cabishop@buffalo.edu
Description:
This study enrolls adults who have had heart failure or heart attack or who are generally healthy. The purpose of this study is to learn more about how these types of cardiovascular issues happen at a biological level. We will do that by looking at the immune cells in the blood. Read More
Eligibility:
Adults ages 18+
Generally healthy OR are presenting to the hospital with heart failure or acute myocardial infarction (heart attack).
Contact(s)
LISA EAGLER
lavathy@buffalo.edu
+1 716-645-6800
Description:
This study enrolls people who have mitral regurgitation (MR). Mitral regurgitation happens when the heart’s mitral valve does not close tightly. The purpose of this trial is to evaluate a new investigational device called the Tendyne™ Mitral Valve System. The Tendyne Mitral Valve System is designed for the treatment of a diseased, damaged or malfunctioning mitral valve. This trial will collect information on how safe and effective this device is to treat a leaking mitral valve compared to the commercially available MitraClip® System. Read More
Eligibility:
-Adults ages 18+.
-Have symptomatic, moderate-to-severe/severe mitral regurgitation (MR) or severe mitral annular calcification (MAC)
-Your medical providers have decided a transcatheter therapy is more appropriate than open surgery.
Description:
This study is for people undergoing surgery for mitral regurgitation (MR). Mitral regurgitation is a condition when your heart’s mitral valve does not close tightly which causes blood to flow backwards in your heart. The purpose of this study is to learn how safe and effective one value repair system is (the PASCAL System, an investigational device) compared to another one (the MitraClip System). Read More
Eligibility:
Adults ages 18+.
Have severe degenerative mitral regurgitation, and are considered prohibitive risk for mitral valve surgery by your heart team.
Contact(s)
COURTNEY BISHOP
cabishop@buffalo.edu
Description:
This is a research study which will determine whether a series of tests can predict the Read More
Eligibility:
• Coronary artery disease (by cardiac catheterization or definite myocardial infarction)
• ICD implantation for the primary prevention of SCA
• Optimal medical therapy for heart failure [angiotensin converting enzyme inhibitor (ACEI) or angiotensin receptor antagonist (ARA)].
Contact(s)
JOHN CANTY
canty@buffalo.edu
+1 716-829-2663
Natalie Stafford
nstaffor@buffalo.edu
+1 716-829-6115
Description:
This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR) and have Heart Failure symptoms which are not under control despite treatment with current available therapies. The purpose of this study is to compare a new investigational (experimental) device plus optimal drug therapy with optimal drug therapy alone. Read More
Eligibility:
Adults ages 18+
Diagnosed with moderate or greater Tricuspid Regurgitation/Insufficiency with Heart Failure symptoms
Contact(s)
COURTNEY BISHOP
cabishop@buffalo.edu
Description:
This study enrolls adults who have had a recent stroke or stroke symptoms. The purpose of this study is to compare how well the study drug (tenecteplase) works for people with stroke symptoms. Read More
Eligibility:
-Adults ages 18+.
-Have been diagnosed with a stroke or stroke symptoms.
-Please contact the research team for other eligibility criteria.
Showing Active Clinical Trials
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