Due to COVID-19, new enrollment in research studies will be greatly limited.
If you are interested in a study, there may be a longer waiting period to receive a response to your inquiry.
View the guidance for research participants for additional information.
This study enrolls people who have had a stroke or who have epilepsy who are being seen at Buffalo General Hospital. We want to learn more about how a patient’s understanding of the disease, treatment and other factors prevent future medical events. Read More
Adults ages 18+.
Must have confirmed diagnosis of stroke or seizure disorder.
Presents for stroke or seizure at Buffalo General Medical Center.
This study enrolls people with atrial fibrillation (AF) who have had a recent brain bleed (with in 4 months). The purpose of this study is to compare the effects of apixaban (also known as Eliquis®) with aspirin in patients to see which is better in preventing strokes and death. Read More
-Adults ages 18+.
-Diagnosed with Intracerebral hemorrhage (ICH).
-Have non-valvular atrial fibrillation or atrial flutter.
This study enrolls people who are hospitalized with acute heart failure. The purpose of this study is to learn if it is safe and effective to start the study medication (empagliflozin) while a person is in the hospital for acute heart failure. Read More
-Adults ages 18+
-Currently hospitalized with primary diagnosis of acute heart failure
-Evidence of left ventricular ejection fraction, either reduced or preserved, in the 12 months
This study enrolls adults with tricuspid valve regurgitation. This is a condition where the valve between the two right heart chambers does not close correctly. The purpose of this study is to learn about patients' preferences for managing and treating this condition. The results of the study may help other patients with tricuspid valve disease, as well as healthcare professionals providing care to patients with tricuspid valve disease, in the future. Read More
Adults ages 21+
Diagnosis of tricuspid valve regurgitation (moderate or greater)
Untreated or receiving medical management and still symptomatic
This study enrolls people who have been diagnosed with an ischemic stroke, a type of stroke where an artery in your brain has been blocked by a blood clot. The purpose of this study is to collect information (data) on medical devices used in the procedure to remove the blood clot and look at the success and related to different medical devices. Read More
Adults ages 18+
Diagnosed with ischemic stroke and planning to undergo procedure to remove blood clot
This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR) and have Heart Failure symptoms which are not under control despite treatment with current available therapies. The purpose of this study is to compare a new investigational (experimental) device plus optimal drug therapy with optimal drug therapy alone. Read More
Adults ages 18+
Diagnosed with moderate or greater Tricuspid Regurgitation/Insufficiency with Heart Failure symptoms
The purpose of this research study is to compare the use of apixaban to aspirin in patients with unexplained strokes and atrial cardiopathy to see which is better at prevention of future strokes. Read More
Adults ages 45+
Have been diagnosed with an ischemic stroke of undetermined cause in the last 120 days.
Currently admitted to Gates Vascular Institute.
This study enrolls people who have been diagnosed with a subarachnoid hemorrhage (SAH), a type of brain bleed. The most common complication after SAH is blood vessel narrowing (vasospasm) in the brain. The purpose of this study is to find out if an investigational (experimental) device, which has not yet been approved by the FDA, is safe and can help treat patients who develop vasospasm after treatment of a SAH. Read More
People ages 18+
Developed vasospasm complications after treatment for SAH
This study enrolls people who have had a stroke in the past 2 weeks. This research is being done to figure out whether treatment for sleep apnea in people who have had a stroke or transient ischemic attack (TIA or "mini stroke"), improves recovery from stroke and helps prevent future stroke, heart problems, and death. Read More
Adults ages 18+.
Are at an inpatient at an enrolling site (Buffalo General Hospital or Gates Vascular Institute).
Have had an ischemic stroke or TIA within the past 14 days.
Use a CPAP machine.
This study enrolls adults ages 18-65 who have the symptoms of an ischemic stroke. An ischemic stroke is caused by a clot in a blood vessel that blocks blood flow to a certain part of the brain. The purpose of this study is to learn more about if people with this type of stroke do better when their blockage is removed within 24 hours of the stroke starting. Read More
Adults ages 18-65.
Presenting to the hospital with symptoms consistent with an acute ischemic stroke.