Due to COVID-19, new enrollment in research studies will be greatly limited.
If you are interested in a study, there may be a longer waiting period to receive a response to your inquiry.
View the guidance for research participants for additional information.
This study enrolls adults in the Emergency Department who will be receiving a blood test. The purpose of this research study is to test blood with a new meter to determine if it is accurate. The meter has not yet been approved for use but the FDA believes that this is a low risk device to obtain and test blood samples. The meter is called the StatStrip Lactate, Hemoglobin, and Hematocrit Meter and it tests the amount of lactate, hemoglobin and hematocrit in your system using a drop of blood. Read More
Adults ages 18+
In the Emergency Department at ECMC or a Kaleida Health Facility
Will be receiving a blood test during the course of care
This is a single-center, randomized, open label, placebo controlled clinical trial. Patient who visit our ER and needs blood work or IV line placement may be eligible for the study. Subject enrolled in the study will have an equal chance to be assigned into one of the four study groups for pain relief during the needle stick, i.e. shot blocker, buzzy bee, vapocoolant, or placebo. Totally 220 subjects will be enrolled in the study, with 55 in each group. The PI hypothesizes that the Vapocoolant may not be as effective as the buzzy bee or shot blocker in pain relief. Read More
Children ages 6-18 years old.
Visiting ED at Oishei Children's Hospital and need blood work or IV line placement.
This study enrolls adults ages 18-65 who have the symptoms of an ischemic stroke. An ischemic stroke is caused by a clot in a blood vessel that blocks blood flow to a certain part of the brain. The purpose of this study is to learn more about if people with this type of stroke do better when their blockage is removed within 24 hours of the stroke starting. Read More
Adults ages 18-65.
Presenting to the hospital with symptoms consistent with an acute ischemic stroke.
This study enrolls adults who have had a severe traumatic brain injury (TBI) who are in the Intensive Care Unit (ICU) at ECMC. The purpose of this study is to learn how the timing of giving patients with TBI a tracheostomy (putting a short tube directly into the trachea/windpipe through a small incision) can impact rates of ventilator associated pneumonia. Your participation in this study will involve receiving a tracheostomy as part of your usual care. If your doctors determine that you could benefit from a tracheostomy early in your care and you agree to the procedure, the tracheostomy will be performed. The study takes place at Erie County Medical Center. Compensation is not available for this study. Read More
Adults age 18+. Currently admitted to the Intensive Care Unit (ICU) at ECMC in Buffalo, NY. Diagnosed with traumatic brain injury (TBI) resulting from blunt or penetrating trauma. Requires endotracheal intubation to secure airway.
We are looking for adults ages 18+ coming into Kaleida Health’s Gates Vascular Institute who have recently had a certain kind of mild stroke for this study (acute ischemic stroke that presents with mild symptoms). You would need to be enrolled into the study within 6 hours of when your symptoms begin. The purpose of this study is to find out which factors associated with the stroke make the condition worse. This will help us identify high-risk patients in the future. You will participate in this study for about 90 days. During the study you will not be asked to do anything additional- all the procedures involved in this study are routinely done with patients with stroke. If you decide to be in this study, we will gather data (for example, your history and vital signs) from your medical Read More
Diagnosed with acute ischemic stroke.
At Kaleida Health-Gates Vascular Institute.
Enrolled within 6 hours from when symptoms begin.
This study enrolls children who are admitted to the pediatric intensive care unit. The purpose of this study is to learn about the effects of blood transfusion on multiple organ dysfunction syndrome (MODS). Patient’s participation in this study will involve giving blood and urine samples and chest x-rays. During the study, we will store and analyze participant’s blood and urine to measure certain protein levels and collect information about their genetic material (DNA). Compensation is not available for this study. Read More
Children ages 1 month to 18 years who are admitted to the pediatric intensive care unit.
Critically ill pediatric patients receiving blood transfusion who have an expected length of stay after transfusion in the ICU of more than 24 hours (based on the best judgment of the attending ICU staff).
This study enrolls people who are in the Emergency Department. The purpose of this study is to test a device (made by the study sponsor, Forest Devices) that may be able to tell if someone is having a stroke. This device is portable, so it might someday be used on an ambulance to give caregivers early information on whether a patient who seems to be having a stroke is actually having a stroke or not. The device is painless and uses electrodes to gather information about brain activity. Read More
Adults ages 18+ who have been brought to a participating Emergency Department with the signs of a stroke.
This study enrolls children admitted to the intensive care unit with traumatic brain injury (TBI). The purpose of this study is to see if the forehead probe being studied can accurately monitor pressure and brain oxygen levels. Read More
Children ages 0-18.
Have been admitted to the pediatric intensive care unit at Oishei Children’s Hospital with traumatic brain injury and an ICP monitor.
This study enrolls trauma physicians. The purpose of this study is to learn more about how trauma physicians treat post traumatic mass transfusion diuresis, which is a way to remove excess fluid from a patient. Read More
Member of EAST (Eastern Association for the Surgery of Trauma)
This study enrolls children ages 1-21 who come to the Emergency Department with head trauma. The purpose of this study is to learn about the safety of giving an anti-nausea medication called Zofran to people who have nausea and/or vomiting after head trauma. Read More
Children ages 1-21.
Have presented to the Emergency Department at John R. Oishei Children’s Hospital with head trauma.
Require a dose of Ondansetron for nausea or vomiting.