The University at Buffalo (UB) is looking for healthy volunteers to participate in an MRI (magnetic resonance imaging) and PET (positron emission tomography) scan study. The goal of this study is to see how microglia cells (found in the brain and spinal cord) relate to the development of multiple sclerosis. Read More
65 years old
Not currently pregnant
Have not been diagnosed with any medical conditions affecting the brain.
The University at Buffalo (UB) Department of Rehabilitation Sciences is looking for adult volunteers with and without spinal cord injuries to participate in an exercise study. The goal of the study is to learn more about the brain and bodily responses to exercise in people with and without spinal cord injuries. The results of this study will hopefully improve the quality of life for adults with spinal cord injuries. Read More
Adults between the ages of 18-55 years old
Adults with a spinal cord injury (at least 6 months after the initial injury)
Adults without a spinal cord injury
Reliable transportation to attend two study visits on the UB South Campus (at Main Street and Bailey Avenue)
We are looking for adults ages 18-40 for this study. We are looking for people in general good health and also people who have had a history of blast exposure and blunt head trauma. The purpose of this study is to learn more about balance in people with a history of blast exposure and blunt head trauma compared to healthy people. You will participate in this study for one session that lasts about 3 hours. During the study you will complete balance, vision, and stability tests in our lab. Study visit takes place in the Department of Rehabilitation Science lab at UB's South Campus. Participants will be compensated. Read More
-Adults ages 18-40.
-Generally healthy OR have had a history of impact brain injury/head trauma in past ten years.
This study enrolls adults with Relapsing Multiple Sclerosis. The purpose of this study is to learn about changes in cognition that happen while being treated with the experimental medication RPC1063 (also known as ozanimod). Read More
- Adults ages 18-65.
- Have at least 5 years since time of RMS diagnosis.
- Have no clinically relevant cardiovascular conditions.
This study is to evaluate the long-term safety and tolerability of daily valbenazine (20, 40, 60, or 80mg) for the treatment of chorea associated with Huntington's Disease (HD) for up to 104 weeks. This study will enroll approximately 120 medically stable male and female subjects with HD who previously completed study drug dosing during the maintenance period as well as the study visit at Week 14 for Study NBI-98854-HD3005. Read More
To participate in this study, subjects must meet the following criteria:
1. Participated in Study NBI-98854-HD3005 and
a) Study drug dosing completion of Study NBI-98854-HD3005, as demonstrated by completed study drug dosing during the dose maintenance period as well as the study visit at Week 14.
b) Early terminated Study NBI-98854-HD3005 for administrative reasons due to COVID-19...
We plan to collect urine samples from patients with Parkinson's Disease, from which we can model the Parkinson's brain. Genetically, the neurons we generate from the urine will match that of the patient donor, making them an ideal way to screen for markers of disease. We will use our urine-derived neurons to assess differences between patient and healthy control cells, as well as a comparison of time-points from individual patients. This study will allow us to gain a clearer understanding of the altered neurochemical state that is so difficult to assess in Parkinson’s patients. Read More
Diagnosis of Parkinson's Disease (or spousal control), either with or without resting tremor
Aged between 40 and 99 years of age
Absence of renal disease
Participants with or without multiple sclerosis are needed for this research study on audio-visual cognition. Participants will be asked to complete some short questionnaires and cognitive tasks over the span of approximately 2-3 hours. All testing will be completed in one session at the University at Buffalo's Division of Cognitive and Behavioral Neurosciences Laboratories. Read More
-Age range 20-65 years
-Normal Hearing and Vision
-DO NOT have the following: severe psychiatric disorder, alcohol or substance abuse or dependence, history of traumatic head injury, neurological disturbances other than multiple sclerosis.
We invite you to participate in this research study because you've been diagnosed with a spinal condition requiring surgery using pedicle screw instrumentation in your lumbar spine. Your surgeon plans to use the VersaTie tether to prevent breakdown above your spine surgery. The VersaTie tether provides a gradual transition from the unfused to fused spine. The study procedure will take place at Gates Vascular Institute. Read More
1. >18 years of age at the time of treatment
2. EOS full body or standing 36” AP & Lateral images of entire spine
3. Posterior spine fusion with pedicle screw fixation construct of 5 or more levels
4. Pedicle screw fixation to be supplemented proximally with NuVasive VersaTie system
5. Upper instrumented vertebra (UIV) terminating at a newly instru...
Adult patients with cerebral palsy will be walking on ground and a treadmill. Participants will wear a belt on their waist with sensors connected to a robot. There will be unpleasant sounds generated to provide cues to change walking pattern. Study will take place at UB for six sessions and will take two hours for each session. Read More
This study enrolls people who have suffered a stroke in the past 24 hours. The purpose of this study is to learn if a patient can benefit from a clot removal procedure if they have a stroke scale of 5 or lower. Read More
-Adults ages 18+
-Diagnosed with acute ischemic stroke and have an objective neurological deficit.