Due to COVID-19, new enrollment in research studies will be greatly limited.
If you are interested in a study, there may be a longer waiting period to receive a response to your inquiry.
View the guidance for research participants for additional information.
We are looking for people with MS who have dysarthria and their caregivers for this research study. The purpose of this study is to find out is a software application can improve quality of life by making speech easier to understand. Read More
Adults ages 18-75.
Have been diagnosed with MS and moderate-severe dysarthria.
Have an iPhone or iPad.
This study enrolls people who have been diagnosed with an ischemic stroke, a type of stroke where an artery in your brain has been blocked by a blood clot. The purpose of this study is to collect information (data) on medical devices used in the procedure to remove the blood clot and look at the success and related to different medical devices. Read More
Adults ages 18+
Diagnosed with ischemic stroke and planning to undergo procedure to remove blood clot
This study enrolls people who have been diagnosed with Idiopathic Intracranial Hypertension (IIH), or high pressure in the brain due to unknown reasons. The purpose of this study is to find out if an investigational (experimental) device, which has not been approved by the FDA yet, is safe and can help treat patients who suffer from vision problems and headaches related to IIH. The device being tested is a stent that will reopen the narrowed veins in the brain as other small studies have shown this to be beneficial to patients with IIH. Read More
People ages 18+
Diagnosis of IIH with symptoms of headaches or vision problems
The purpose of this research study is to compare the use of apixaban to aspirin in patients with unexplained strokes and atrial cardiopathy to see which is better at prevention of future strokes. Read More
Adults ages 45+
Have been diagnosed with an ischemic stroke of undetermined cause in the last 120 days.
Currently admitted to Gates Vascular Institute.
This study enrolls adults aged 18-75 who are diagnosed with unwanted movements (chorea) associated with Huntington Disease (HD). The purpose of this study is to learn how well Valbenazine works in reducing these unwanted movements, and learn more about the safety and side effects of this medication. Valbenazine has already been approved by the FDA since April 2017 for the treatment of side effects related to other medications. Read More
Male and female adults aged 18-75 years
Diagnosis of Huntington Disease
Able to walk (assist devices such as cane or walker are allowed)
Negative pregnancy test for females (determined by blood work at first visit)
Sexually active adults of childbearing age must agree to consistently use birth control methods
Able to read and understand English
This study enrolls people who have had a stroke in the past 2 weeks. This research is being done to figure out whether treatment for sleep apnea in people who have had a stroke or transient ischemic attack (TIA or "mini stroke"), improves recovery from stroke and helps prevent future stroke, heart problems, and death. Read More
Adults ages 18+.
Are at an inpatient at an enrolling site (Buffalo General Hospital or Gates Vascular Institute).
Have had an ischemic stroke or TIA within the past 14 days.
Use a CPAP machine.
This study enrolls adults ages 18-65 who have the symptoms of an ischemic stroke. An ischemic stroke is caused by a clot in a blood vessel that blocks blood flow to a certain part of the brain. The purpose of this study is to learn more about if people with this type of stroke do better when their blockage is removed within 24 hours of the stroke starting. Read More
Adults ages 18-65.
Presenting to the hospital with symptoms consistent with an acute ischemic stroke.
This study enrolls adults who have had a severe traumatic brain injury (TBI) who are in the Intensive Care Unit (ICU) at ECMC. The purpose of this study is to learn how the timing of giving patients with TBI a tracheostomy (putting a short tube directly into the trachea/windpipe through a small incision) can impact rates of ventilator associated pneumonia. Your participation in this study will involve receiving a tracheostomy as part of your usual care. If your doctors determine that you could benefit from a tracheostomy early in your care and you agree to the procedure, the tracheostomy will be performed. The study takes place at Erie County Medical Center. Compensation is not available for this study. Read More
Adults age 18+. Currently admitted to the Intensive Care Unit (ICU) at ECMC in Buffalo, NY. Diagnosed with traumatic brain injury (TBI) resulting from blunt or penetrating trauma. Requires endotracheal intubation to secure airway.
This study enrolls adults who are having a cardiac or cerebrovascular procedure that uses a device called a transcranial doppler. This study is collecting data to look at the changes in blood flow during these procedures. The data collected will help researchers develop techniques and strategies to minimize risk for stroke for future patients. Your participation in the study will not involve anything in addition to the care you are already getting- the study collects information that is already being collected as part of your care. We expect that you will be in this research study for few days until your discharge from the hospital up to your 3 month follow up visit. This study takes place only at Buffalo General Medical Center and Gates Vascular Institute. Compensation is not available for this study. Read More
Patients who have had a cardiac or cerebrovascular procedure using TCD monitoring at Buffalo General Medical Center or Gates Vascular Institute.
Only patients who have been invited to join this study by a study team member may enroll.
We are looking for adults ages 18+ coming into Kaleida Health’s Gates Vascular Institute who have recently had a certain kind of mild stroke for this study (acute ischemic stroke that presents with mild symptoms). You would need to be enrolled into the study within 6 hours of when your symptoms begin. The purpose of this study is to find out which factors associated with the stroke make the condition worse. This will help us identify high-risk patients in the future. You will participate in this study for about 90 days. During the study you will not be asked to do anything additional- all the procedures involved in this study are routinely done with patients with stroke. If you decide to be in this study, we will gather data (for example, your history and vital signs) from your medical Read More
Diagnosed with acute ischemic stroke.
At Kaleida Health-Gates Vascular Institute.
Enrolled within 6 hours from when symptoms begin.