The University at Buffalo (UB) School of Dental Medicine is looking for volunteers to join a gum disease study. The study aims to learn more about how harmful bacteria grow in the mouth and cause periodontal (gum) disease. We are interested in Porphyromonas gingivalis (P. ginivalis), a pathogen involved in gum disease. Read More

Adults aged 25 years or older Have at least 16 natural teeth Have the bacterium Porphyromonas gingivitis in their mouth Have gum disease (which will be determined by study staff) Do not wear braces or other orthodontic equipment Have not had periodontal treatment or surgery in the past year Not currently pregnant

The University at Buffalo (UB) Department of Neurology is recruiting healthy adults and those with multiple sclerosis (MS) for a study. The goal of the study is to examine a new test of processing speed (or how quickly the brain understands and responds to information) that was developed for people diagnosed with MS. Read More

-Adults 18 years or older
-Have been diagnosed with multiple sclerosis (MS) OR are healthy adults
-Speak English

This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR). The purpose of this study is to look at the safety and effectiveness of this new investigational device compared to the standard medical treatment. Read More

Adults ages 18+
Diagnosed with Tricuspid Regurgitation/Insufficiency

This study enrolls people who have mitral regurgitation (MR). Mitral regurgitation happens when the heart’s mitral valve does not close tightly. The purpose of this trial is to evaluate a new investigational device called the Tendyne™ Mitral Valve System. The Tendyne Mitral Valve System is designed for the treatment of a diseased, damaged or malfunctioning mitral valve. This trial will collect information on how safe and effective this device is to treat a leaking mitral valve compared to the commercially available MitraClip® System. Read More

-Adults ages 18+.
-Have symptomatic, moderate-to-severe/severe mitral regurgitation (MR) or severe mitral annular calcification (MAC)
-Your medical providers have decided a transcatheter therapy is more appropriate than open surgery.

This study enrolls children and adults who have tested positive for COVID-19. The purpose of this study is to collect and bank blood samples of people who have COVID-19. We will analyze these samples to understand more about the virus. Read More

Adults or children
Positive for SARS-CoV-2 or highly suspicious for SARS-CoV-2 (symptoms with known contact).

This study is for people undergoing surgery for mitral regurgitation (MR). Mitral regurgitation is a condition when your heart’s mitral valve does not close tightly which causes blood to flow backwards in your heart. The purpose of this study is to learn how safe and effective one value repair system is (the PASCAL System, an investigational device) compared to another one (the MitraClip System). Read More

Adults ages 18+.
Have severe degenerative mitral regurgitation, and are considered prohibitive risk for mitral valve surgery by your heart team.

This study enrolls healthy adults. The purpose is to determine a standard for how healthy people walk so that we can better help patients who have difficulty walking. Read More

Healthy adults ages 20-80
English speaking
Able to walk without assistance.

This study enrolls healthy adults. The purpose of this study is to learn how people use memories and make decisions about their behavior. Read More

Healthy adults ages 18-64.
English spoken as first language.
USA residents.
Cannot be pregnant.

This study uses a phone app to track people’s life values and goals. It aims to help people improve their quality of life by completing their goals with the help of trained life coaches. It includes two in-person visits, a few phone check-ins, short tests, and questionnaires. Read More

60+ years old, Own smart phone, and Have no history of substance use problems or mental health/ neurological conditions.

We are looking for adults with type 1 diabetes for a research study. The purpose of the study is to see how well an already approved treatment for type 2 diabetes works for people with type 1 diabetes. Read More

Adults ages 18+.
Diagnosed with Type 1 diabetes.
Currently using an insulin pump or multiple daily injections of insulin.