Search and volunteer to participate in these available studies at UB. Your participation in research doesn't just benefit you, it helps advance healthcare for our entire community.

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Showing 11 - 20 of 41 Clinical Trials
Description:
This study enrolls adults who are scheduled to have an aortic valve replacement for disease the aortic valve called aortic stenosis. The Evolut PRO and Evolut PRO+ systems are FDA approved for treating aortic stenosis, so in this study we just want to collect data. The purpose of this study is to learn more about how well this device works. Read More
Eligibility:
-Adults ages 18+.
-Have symptoms from aortic valve stenosis.
-Will be having aortic valve replacement.
Contact(s)
ROBIN STEIN
rmstein3@buffalo.edu
+1 716-888-4859
Description:
This study enrolls people who have mitral regurgitation (MR). Mitral regurgitation happens when the heart’s mitral valve does not close tightly. The purpose of this trial is to evaluate a new investigational device called the Tendyne™ Mitral Valve System. The Tendyne Mitral Valve System is designed for the treatment of a diseased, damaged or malfunctioning mitral valve. This trial will collect information on how safe and effective this device is to treat a leaking mitral valve compared to the commercially available MitraClip® System. Read More
Eligibility:
-Adults ages 18+.
-Have symptomatic, moderate-to-severe/severe mitral regurgitation (MR) or severe mitral annular calcification (MAC)
-Your medical providers have decided a transcatheter therapy is more appropriate than open surgery.
Description:
This study enrolls people who have had a stroke or who have epilepsy who are being seen at Buffalo General Hospital. We want to learn more about how a patient’s understanding of the disease, treatment and other factors prevent future medical events. Read More
Eligibility:
Adults ages 18+.
Must have confirmed diagnosis of stroke or seizure disorder.
Presents for stroke or seizure at Buffalo General Medical Center.
Contact(s)
Description:
This study enrolls adults ages 18-65 who have the symptoms of an ischemic stroke. An ischemic stroke is caused by a clot in a blood vessel that blocks blood flow to a certain part of the brain. The purpose of this study is to learn more about if people with this type of stroke do better when their blockage is removed within 24 hours of the stroke starting. Read More
Eligibility:
Adults ages 18-65.
Presenting to the hospital with symptoms consistent with an acute ischemic stroke.
Contact(s)
JENNIFER GAY
jgay@ubns.com
+1 716-888-4811
Description:
We are looking for adults ages 18+ coming into Kaleida Health’s Gates Vascular Institute who have recently had a certain kind of mild stroke for this study (acute ischemic stroke that presents with mild symptoms). You would need to be enrolled into the study within 6 hours of when your symptoms begin. The purpose of this study is to find out which factors associated with the stroke make the condition worse. This will help us identify high-risk patients in the future. You will participate in this study for about 90 days. During the study you will not be asked to do anything additional- all the procedures involved in this study are routinely done with patients with stroke. If you decide to be in this study, we will gather data (for example, your history and vital signs) from your medical Read More
Eligibility:
Age 18+.
Diagnosed with acute ischemic stroke.
At Kaleida Health-Gates Vascular Institute.
Enrolled within 6 hours from when symptoms begin.
Contact(s)
ELIZABETH SHISLER
eshisler@upa.chob.edu
+1 716-929-9681
Description:
This study is for people undergoing surgery for mitral regurgitation (MR). Mitral regurgitation is a condition when your heart’s mitral valve does not close tightly which causes blood to flow backwards in your heart. The purpose of this study is to learn how safe and effective one value repair system is (the PASCAL System, an investigational device) compared to another one (the MitraClip System). Read More
Eligibility:
Adults ages 18+.
Have severe degenerative mitral regurgitation, and are considered prohibitive risk for mitral valve surgery by your heart team.
Contact(s)
COURTNEY BISHOP
cabishop@buffalo.edu
Description:
This study enrolls people who have had or are about to have certain procedures for stroke. The purpose of this research study is to learn more about how different devices that are used to remove blood clots work on different types of clots. Read More
Eligibility:
Adults ages 18+.
Have undergone endovascular thrombectomy treatment for stroke or are going to undergo thrombectomy for removal of peripheral clot.
Contact(s)
JENNIFER GAY
jgay@ubns.com
+1 716-888-4811
Description:
We are enrolling people who are undergoing a cardiac neurological procedure. The purpose of this study is to collect information from a medical device used in these procedures called the VISOR device. We will collect information before and after a person has a cardio-cerebrovascular procedure to see how well the device detects neurological injury from the procedure. Read More
Eligibility:
-Adults ages 18+.
-Undergoing cardiovascular procedures including trans-aortic valve replacement (TAVR), left atrial appendage closure, electrophysiological ablation, coronary artery bypass grafting (CABG) and valve replacement surgery, with the application of Cerebrotech VISOR.
Contact(s)
ELIZABETH SHISLER
eshisler@upa.chob.edu
+1 716-929-9681
Description:
This study enrolls infants who have a patent ductus arteriosus or ‘PDA’. The purpose of this study is to compare two care methods to determine which is better for treating premature babies with PDA. Read More
Eligibility:
Children (infants) who were born prematurely at 22-28 weeks and 6 days gestational age.
Must have been diagnosed with a PDA (patent ductus arteriosus) and be in the NICU at Oishei Children’s Hospital.
Contact(s)
Emily Li
esli@buffalo.edu
Description:
There is currently no standard way to treat "diastolic" heart failure, also called “heart failure with preserved ejection fraction" (HFpEF). We are looking for adults with HFpEF fora study of the benefits of dapagliflozin (Farxiga). This drug was originally developed for treating diabetes but it also helps rid the body of excess water. Because heart failure causes excess water retention, we want to know if dapagliflozin is safe and effective for treating HFpEF in both diabetic & non-diabetic adults. Read More
Eligibility:
Adults ages 40+
with or without diabetes
diagnosed with "diastolic"; heart failure or "heart failure with preserved ejection fraction" (HFpEF)
Contact(s)
JOSEPH IZZO
jizzo@buffalo.edu
+1 716-898-5234
Showing 11 - 20 of 41 Clinical Trials
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