Sleep SMART: Stroke & Sleep Apnea Study
Protocol: SITE00000123
Full Title
Sleep for Stroke Management and Recovery Trial
Description
This study enrolls people who have had a stroke in the past 2 weeks. This research is being done to figure out whether treatment for sleep apnea in people who have had a stroke or transient ischemic attack (TIA or "mini stroke"), improves recovery from stroke and helps prevent future stroke, heart problems, and death.

You will be in this research study for about 6 months. There are two parts of this study. The first part will help us know if you are eligible to continue in the study. First, we will test you for sleep apnea with a portable respiratory sleep monitor. If you meet the requirements for sleep apnea, you will test a sleep apnea machine for 1 night while in the hospital. If the machine works for you, you will be randomly assigned (like the flip of a coin) to have either the usual medical care for stroke and TIA patients plus CPAP (one group), or the same usual medical care without CPAP (another group), for the next 6 months. You will come in for study visits around 3 months and 6 months after you are randomly assigned to one of the two groups.

Study visits will take place at UBMD Neurology 1001 Main Street Buffalo, NY 14202 or 5851 Main Street in Williamsville.

Technical Description

The primary goals of this study are to determine whether treatment of OSA with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.

Compensation: No
Eligibility
Adults ages 18+.
Are at an inpatient at an enrolling site (Buffalo General Hospital or Gates Vascular Institute).
Have had an ischemic stroke or TIA within the past 14 days.
Use a CPAP machine.
Age Group: Adults
ClinicalTrials.gov: Open Study
Want to Learn More?
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.
Thank you for your interest. This study has restricted recruiting for participants and is not accepting inquiries at this time. If you are interested in learning more about research at UB contact ctsiresearch@buffalo.edu.