Erie County Medical Center is recruiting head and neck cancer survivors for the AQUAx2 study. The goal of this study is to determine how effective a new study drug (AAV2-hAQP1) is at helping with dry mouth (xerostomia) caused by radiation therapy. Read More

Adults over the age of 18 years old Have previously completed radiation therapy for head or neck cancer Have not had head or neck cancer for at least 3 years Have not been diagnosed with any other types of cance

The University at Buffalo (UB) Department of Psychology is looking for adults who have had pain from cancer for a remote study. The goal of the study is to learn more about how cannabis may be used to treat pain from cancer. Read More

Adults 21 years or older Identify as either Black or White Have had cancer in the past 3 years Have had a prescription for opioids and pain for more than 30 days Used/have not used cannabis regularly for the past 3 months

The University at Buffalo (UB) Department of Medicine is recruiting adults diagnosed with prostate cancer for a study. The goal of the study is to see if intermittent fasting (or eating only during certain hours of the day) can help to improve the effectiveness of cancer treatment. Read More

Adults 18 years or older Have been diagnosed with prostate cance

The University at Buffalo is looking for adults needing colorectal surgery for a clinical trial. The goal of this study is to investigate the safety and effectiveness of the COLO-BT (Colorectal Balloon Tube) device for people needing colon resection surgery. Read More

Adults aged 19-80 years old Need colon (rectal) resection surgery

Researchers think the study drug, EPI-7386, may be an effective treatment for metastatic castration-resistant prostate cancer (mCRPC) because the drug works by interfering with the function of the male hormone system that leads to the growth of prostate cancer. Enzalutamide is an androgen receptor inhibitor that works by blocking the action of male hormones (androgens) like testosterone to slow down the growth of prostate cancer. Enzalutamide is approved by the Food & Drug Administration (FDA) and is commonly used as a standard of care option for men with advanced or metastatic castration-resistant prostate cancer. Since EPI-7386 and enzalutamide have not been combined together in humans, we are doing this study to find out whether EPI-7386, in combination with a fixed dose of enzalutamide, compared to standard of care enzalutamide alone, is a safe and effective treatment for men who have mCRPC. Study will be done at Spindrift Clinic location. Read More

1) Males aged 18 years or older
2) Histologically, pathologically, or cytologically confirmed prostate adenocarcinoma
3) Presence of metastatic disease at study entry
4) Naïve to second generation anti-androgens

This study enrolls men with prostate cancer. The purpose of this study is to compare using radium-223 and docetaxel chemotherapy treatment vs. using docetaxel alone in men with Metastatic Castration-Resistant Prostate Cancer (mCRPC). Radium223 has been FDA approved to treat men with prostate cancer that has spread to the bone, but it has not been approved for men with cancer that has spread to soft tissue or in combination with the chemotherapy drug docetaxel. Read More

Adults ages 18+.
Males with progressive Metastatic Prostate Cancer.
Have 2+ bone lesions.

This study enrolls adults diagnosed with head and neck cancer who have plans to complete chemoradiotherapy. The purpose of this study is to learn the best timing for feeding tube placement and speech therapy to create the best quality of life for patients. Read More

Adults ages 18+.
Patients with Head and Neck Cancer being treated at ECMC and Cancer Care WNY.
Patients planning to receive concurrent chemo-radiation therapy.

This study enrolls people who have been diagnosed with head and neck cancer and are being treated with neck radiation therapy. The purpose of this study is to find out the number of people who develop narrowing of their carotid arteries (Carotid Artery Stenosis) due to neck radiation and understand how tobacco use and diabetes effect the worsening of carotid artery stenosis. Read More

Adults age 18+
Diagnosis of neck cancer and undergoing one-sided neck radiation
Must have no history of stroke

This study enrolls adults with head and neck cancer. The purpose of the study is to learn if a light device used in the mouth during chemotherapy and radiation can help prevent oral mucositis. Read More

Diagnosed with cancer (pathologically confirmed squamous cell carcinoma) of the oral cavity, oropharynx, tonsil or base of tongue.
Scheduled to have a continuous course of Intensity-Modulated Radiation Therapy (IMRT) over an estimated 6 to 8 weeks.