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Study for Head and Neck Cancer Survivors with Dry Mouth
Protocol: STUDY00007449
Full Title
A Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of AAV2-hAQP1 Gene Therapy in Participants with Radiation-Induced Late Xerostomia
Description
Erie County Medical Center is recruiting head and neck cancer survivors for the AQUAx2 study. The goal of this study is to determine how effective a new study drug (AAV2-hAQP1) is at helping with dry mouth (xerostomia) caused by radiation therapy.

Participants will be in this study for 1 year. They will be randomly assigned (which happens by chance, like flipping a coin) to one of three study conditions: two groups will receive different concentrations of the study drug and the third group will receive a placebo (which looks like the study drug but does not contain any active medication). Throughout the study, participants will complete physical exams, surveys, saliva/urine collections, and blood draws.
Compensation: Yes
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Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Eligibility
Adults over the age of 18 years old Have previously completed radiation therapy for head or neck cancer Have not had head or neck cancer for at least 3 years Have not been diagnosed with any other types of cancer
Age Group: Adults
Principal Investigator: JENNIFER FRUSTINO
Contact(s)
LYNN JAGODZINSKI
lynnjago@buffalo.edu
+1 716-888-4843
JENNA MILLEMACI
jmmillem@buffalo.edu
+1 716-898-3000
Want to Learn More?

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