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Study for Adults with Compensated Liver Cirrhosis
Protocol: STUDY00008596
Full Title
A phase 3, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of efruxifermin in subjects with compensdated cirrhosis due to nonalcoholic steatohepatitis (NASH)/metabolic dysfunction-associated steatohepatitis (MASH)
Description
The University at Buffalo is recruiting adults living with compensated liver cirrhosis for a 5-year study. People with this diagnosis have scarring on their livers but their livers still function normally.

The study will include 3 months for screening, 5 years of study treatment, and a 30-day follow-up visit. This will involve up to 39 visits to the Study Doctor: every week for the first month, once a month for the following year and a half, and then every 3 months. Each study visit will take about 2 hours.

Participants will be randomly assigned (which happens by chance, like flipping a coin) to one of the following groups:
-Group 1: will receive a placebo (which looks like the study medicine but does not contain any active medication)
-Group 2: will receive 50mg of the study medicine

The placebo/study medicine will be injected by a needle into the soft tissue under the skin in the stomach or upper thigh once a week.

Participants may receive up to $1,650.
Compensation: Yes
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Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Eligibility
-Adults 18 years or older
-Have been diagnosed with liver cirrhosis due to nonalcoholic steatohepatitis (NASH)/metabolic dysfunction-associated steatohepatitis (MASH)
-Not currently pregnant
Age Group: Adults
Principal Investigator: AJAY CHAUDHURI
ClinicalTrials.gov: Open Study
Contact(s)
RICHARD REJMAN
rmrejman@buffalo.edu
+1 716-878-3320

Want to Learn More?

Let us know how the study team can reach you. If you do not hear back within 2 business days, then reach out to the study team directly at the contact information above and someone will assist you.

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