The goal of this study is to evaluate the safety, effectiveness and tolerability of a drug compound (AVP- 786) for the treatment of agitation associated with Alzheimer’s Disease. Alzheimer’s Disease causes loss of brain cells and problems with memory, thinking and behavior. Agitated behaviors, such as irritability and restlessness, physical and verbal aggression, and pacing and wandering are major problems in this condition, can be difficult to manage, and can impact your quality of life. AVP-786 is targeted at treating your agitation behaviors. Caregivers are being asked to take part in this research study because the participants may require assistance to complete study procedures and/or attend study visits. Participation in this study will last for approximately 20 weeks and include site visits throughout the study. Read More
Patients 50 to 90 years of age (inclusive) with clinically significant, moderate-to-severe agitation for at least 2 weeks prior to screening that interferes with daily routine per the Investigator's judgment, and who require pharmacotherapy for the treatment of agitation per the Investigator's judgment after an evaluation of reversible factors and a course of nonpharmacological interventions.
This study enrolls older adults with Alzheimer’s Disease (AD). The purpose of the study is to learn whether the study drug, GV-971, can help the thinking (cognition) and functioning of people with AD. Read More
-Adults ages 50-85.
-Mild to moderate Alzheimer's Disease.
-Please contact our team to learn whether you or your loved one may be a good match for this study.
This study enrolls adults ages 55-90 who have concerns about memory. The purpose of the Memory Improvement Through Nicotine Dosing (MIND) study is to learn whether Nicotine absorbed through the skin through a daily nicotine patch improves attention, learning, and memory in folks with mild cognitive impairment. Read More
Adults ages 55-90.
Must be a non-smoker.
Must have a memory concern as reported by participant, study partner, or clinician.
Study Partner is available who has frequent contact with the participant (e.g. an average of 10 hours per week or more), and can accompany the participant to most visits to answer questions about the participant.
We are looking for healthy adult volunteers OR people with Alzheimer's disease/mild cognitive impairment for a research study. The purpose of this study is to find out what puts people at risk for the loss of insight that is in seen in people with memory problems. Read More
Adults ages 50+.
Have at least 9 years of education.
Generally healthy with no history of cognitive impairment
OR have been diagnosed with Alzheimer's disease or Mild Cognitive Impairment.
This study enrolls older adults who have had changes in memory. The purpose of this study is to learn whether the study medication, donanemab, can slow the progression of Early Alzheimer’s Disease. Read More
Adults ages 60-85.
Have had gradual, progressive changes in memory.