ENDOLOW: Endovascular Therapy for Low NIHSS Ischemic Strokes
This study enrolls people who have suffered a stroke in the past 24 hours. The purpose of this study is to learn if a patient can benefit from a clot removal procedure if they have a stroke scale of 5 or lower.
Typically, the thrombectomy procedure is used to treat a stroke for people who have a National Institute of Health Stroke Scale (NIHSS) of 6 points or higher. The higher the score, the worse the stroke is. In this study, the thrombectomy procedure will be done on patients who have a NIHSS of 5 or lower to see if the procedure can help them recover better from the stroke. The FDA cleared device called EmboTrap will be used during the procedure. If you participate in this study, you will be randomly assigned (like the flip of a coin) to have the procedure or to have the usual care for a stroke. After the procedure, you will be in this study for about 3 months and will have follow up calls and visits during that time.
Study takes place at Kaleida Health Facilities including Gates Vascular Institute and Buffalo General Medical Center and also at UBMD Neurosurgery clinic.
To test efficacy and safety of immediate mechanical thrombectomy (iMT) versus initial medical management (iMM) in patients presenting within 8 hours of onset with cerebral ischemia in the setting of proximal large vessel occlusions (LVO) and low baseline NIHSS scores (NIHSS 0-5).
-Adults ages 18+
-Diagnosed with acute ischemic stroke and have an objective neurological deficit.
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If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email firstname.lastname@example.org and someone will assist you.