Study for Kidney Donors and Kidney Recipients
Protocol: SITE00000073
Full Title
APOL1 Long-term Kidney Transplant Outcomes Network
Description
This study enrolls adults and children who have had a recent kidney transplant. The purpose of this study is to improve outcomes after kidney donation and kidney transplantation by learning about how a specific gene may affect people.

If you decide to participate, you will be asked to provide a small sample of blood and/or urine after your kidney transplant has been performed. Your medical care will otherwise not change.

Compensation is not available.

Technical Description

APOLLO is an observational study designed to assess the impact of renal-risk variants in the APOL1 gene on the functional outcomes of kidneys transplanted from living and deceased donors with recent African ancestry and on the kidney function of living kidney donors with recent African ancestry in a prospective manner. In this protocol, recent African ancestry is broadly defined as African American, Afro-Caribbean, Hispanic black, and African.
APOLLO has several objectives. The primary objective is to determine whether the presence of APOL1 renal-risk variants in a kidney donor shortens death-censored renal allograft survival.
Compensation: No
Eligibility
Adults or children who have undergone kidney transplantation or kidney donation.
Reside in US or Puerto Rico.
Age Group: Adults
Principal Investigator: LIISE KAYLER
ClinicalTrials.gov: Open Study
Contact(s)
Danielle Wittek
dwittek@buffalo.edu
+1 716-361-8500
Want to Learn More?
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the contact information above or email ctsiresearch@buffalo.edu and someone will assist you.