We are looking for people with MS who have dysarthria and their caregivers for this research study. The purpose of this study is to find out is a software application can improve quality of life by making speech easier to understand. Read More
Adults ages 18-75.
Have been diagnosed with MS and moderate-severe dysarthria.
Have an iPhone or iPad.
This study enrolls people who have been diagnosed with Idiopathic Intracranial Hypertension (IIH), or high pressure in the brain due to unknown reasons. The purpose of this study is to find out if an investigational (experimental) device, which has not been approved by the FDA yet, is safe and can help treat patients who suffer from vision problems and headaches related to IIH. The device being tested is a stent that will reopen the narrowed veins in the brain as other small studies have shown this to be beneficial to patients with IIH. Read More
People ages 18+
Diagnosis of IIH with symptoms of headaches or vision problems
This study enrolls adults ages 18-65 who have the symptoms of an ischemic stroke. An ischemic stroke is caused by a clot in a blood vessel that blocks blood flow to a certain part of the brain. The purpose of this study is to learn more about if people with this type of stroke do better when their blockage is removed within 24 hours of the stroke starting. Read More
Adults ages 18-65.
Presenting to the hospital with symptoms consistent with an acute ischemic stroke.
This study enrolls adults who have had a severe traumatic brain injury (TBI) who are in the Intensive Care Unit (ICU) at ECMC. The purpose of this study is to learn how the timing of giving patients with TBI a tracheostomy (putting a short tube directly into the trachea/windpipe through a small incision) can impact rates of ventilator associated pneumonia. Your participation in this study will involve receiving a tracheostomy as part of your usual care. If your doctors determine that you could benefit from a tracheostomy early in your care and you agree to the procedure, the tracheostomy will be performed. The study takes place at Erie County Medical Center. Compensation is not available for this study. Read More
Adults age 18+. Currently admitted to the Intensive Care Unit (ICU) at ECMC in Buffalo, NY. Diagnosed with traumatic brain injury (TBI) resulting from blunt or penetrating trauma. Requires endotracheal intubation to secure airway.
This study enrolls adults who are having a cardiac or cerebrovascular procedure that uses a device called a transcranial doppler. This study is collecting data to look at the changes in blood flow during these procedures. The data collected will help researchers develop techniques and strategies to minimize risk for stroke for future patients. Your participation in the study will not involve anything in addition to the care you are already getting- the study collects information that is already being collected as part of your care. We expect that you will be in this research study for few days until your discharge from the hospital up to your 3 month follow up visit. This study takes place only at Buffalo General Medical Center and Gates Vascular Institute. Compensation is not available for this study. Read More
Patients who have had a cardiac or cerebrovascular procedure using TCD monitoring at Buffalo General Medical Center or Gates Vascular Institute.
Only patients who have been invited to join this study by a study team member may enroll.
We are looking for adults ages 18+ coming into Kaleida Health’s Gates Vascular Institute who have recently had a certain kind of mild stroke for this study (acute ischemic stroke that presents with mild symptoms). You would need to be enrolled into the study within 6 hours of when your symptoms begin. The purpose of this study is to find out which factors associated with the stroke make the condition worse. This will help us identify high-risk patients in the future. You will participate in this study for about 90 days. During the study you will not be asked to do anything additional- all the procedures involved in this study are routinely done with patients with stroke. If you decide to be in this study, we will gather data (for example, your history and vital signs) from your medical Read More
Diagnosed with acute ischemic stroke.
At Kaleida Health-Gates Vascular Institute.
Enrolled within 6 hours from when symptoms begin.
This study enrolls patients of UBMD Orthopedics and Sports Medicine who have recently had a concussion. The purpose of this study use eye tracking software to find out if eye movement is connected to recovery time from concussions. Our goal is to find better ways to diagnose concussions and understand how severe they are. Read More
-Adults and children ages 14-40.
-Physician had diagnosed a concussion within the past 10 days.
-Patient of UBMD Orthopedics and Sports Medicine clinic.
This study enrolls people with advancing Relapsing Multiple Sclerosis (RMS). The purpose of the study is to see how safe and how well tolerated changing from one MS medication to siponimod (an investigational drug for MS) will be. Read More
Adults ages 18+.
Diagnosed with Relapsing Multiple Sclerosis (RMS).
This study enrolls people who have had or are about to have certain procedures for stroke. The purpose of this research study is to learn more about how different devices that are used to remove blood clots work on different types of clots. Read More
Adults ages 18+.
Have undergone endovascular thrombectomy treatment for stroke or are going to undergo thrombectomy for removal of peripheral clot.