Novel Clinical and Translational Methodologies Pilot Projects
The objective of the Novel Clinical and Translational Methodologies Pilot Projects is to provide resources to develop new methodologies that are needed to perform clinical and translational research. The scope of projects could include new measurement techniques or devices, new translational methodologies, methods for biomarkers or phenotyping, determining cost-effectiveness, new approaches to clinical trial design and analysis of clinical research, clinical informatics for longitudinal studies or meta-analytic approaches to treatment evaluation, predictive toxicology, or ethics research specific to populations. Funding will be awarded on a competitive basis. This program is a component of the Buffalo Clinical and Translational Research Center (Buffalo CTRC) providing resources to stimulate research that will lead to new clinical and translational science and securing external research funds. For this round, we are especially interested in projects with a high risk/high reward profile, projects emphasizing biomedical informatics and projects in research ethics.
All faculty (including investigators at Roswell Park Cancer Institute and Hauptman Woodward Institute) are eligible. Proposed projects must be new research. Proposals from investigators who have never received external funding must provide evidence of a meaningful collaboration with a senior funded investigator.
Applications must be submitted as a single PDF by 5:00pm on December 1, 2011 to Dr. Kenneth Tramposch, Associate Vice President for Research, via email to firstname.lastname@example.org.
Terms of Awards:
Applicants can request funding for up to $50,000 for one year projects. Budgets must be consistent with the scope of the proposed project. Proposals must be fully compliant with regulatory guidelines. Annual reports are required detailing the projectâ€™s progress and listing proposals submitted and funding received. On a yearly basis there will be a special Buffalo CTRC sponsored colloquium where awardees will present project results and detail plans for pursuing external funding to continue the project. Awardees will be encouraged to attend Buffalo CTRC sponsored workshops or seminars on the creativity process in research sponsored by the Buffalo CTRC. Award notices are expected to go out February 15, 2012 with award start dates of March 1, 2012.
Funds may not be used for faculty/administrative salaries or tuition. However, all other project costs are eligible with appropriate justification.
Application Format: The proposal must include:
- Project Description (12 point font, single spaced, 3page limit [for items 2-5 below] excluding references)
Project Description should use the following template:
- Project Title and Abstract with a list of all project investigators and their affiliations. (one page)
- Background and Significance of the project.
- Potential impact of the project on the field.
- Specific Aims.
- Overview of approach.
- Budget, Budget Justification and Timeline (one page) â€“ Explain role of each study team member, why Novel Clinical and Translational Methodologies Pilot Projects funds are critical for securing external funding of the larger project. Please note that budget reasonableness is a review criteria.
- NIH-style Biosketch (4 pages) for each investigator showing current and pending support. Proposed projects must not overlap with current funding.
- If a similar proposal has been reviewed and declined by an external funding agency, the reviews must be included, and a one page discussion of how the critiques were dealt in the Novel Clinical and Translational Methodologies Pilot Projects proposal.
- No appendices; other than funding agency reviews, are allowed and will not be reviewed
- Scientific merit
- Significance and impact on the field of the clinical and translational methodologies proposed
- Potential for securing extramural funding
- Rationale and utilization of proposed budget
The proposals will be reviewed by Ad hoc panels of faculty. Final decisions will be made by the Buffalo CTRC Pilot Studies Oversight Committee. Heavy weight will be placed on the potential for securing external funding for the project. We expect to make two awards this year.