Deanna M. Church, Ph.D.
DHHS/NIH/NLM/NCBI
8600 Rockville Pike
Building 38A, rm8N805
Bethesda, MD 20894
church@ncbi.nlm.nih.gov
EDUCATION: Ph.D. in Biological Sciences (1997)
University of California, Irvine
Irvine, California 92717
BA, Liberal Arts, 1990
University of Virginia
Charlottesville, VA 22901
EXPERIENCE: Research Fellow
NCBI
September, 2000 to present
Postdoctoral Fellow with Dr. Greg Schuler
NCBI
September, 1999 to September 2000
Postdoctoral Fellow with Dr. Janet Rossant
Mt. Sinai Hospital, Toronto
July, 1997-September, 1999
Co-Instructor for Cold Spring Harbor Course
Positional Cloning: from Contig to
Candidate, 1996-1998
FUNDING AWARDED: MRC Collaborative Genome Research Project
-awarded July, 1999
MRC Post-doctoral Fellowship
-07/99-09/99
Human Frontiers Science Program
-Long Term Fellowship, 1997-1999
NIH Training Grant (UCI) - 1993-1995
PUBLICATIONS:
International Human Genome Sequencing Consortium (2001) Initial sequencing and analysis of the human genome. Nature 409(15): 860-921.
Wheeler DL, Church DM, Lash AE, Leipe DD, Madden TL, Pontius JU, Schuler GD, Schriml LM, Tatusova TA, Wagner L, Rapp BA. (2001) Database resources of the National Center for Biotechnology Information. Nucleic Acids Res 29(1):11-6.
LePage DF, Church DM, Millie E, Hassold TJ, Conlon RA (2000) Rapid generation of nested chromosomal deletions on mouse chromosome 2. Proc Natl Acad Sci U S A 97(19): 10471-6.
Church DM and Buckler AJ. (1999) Gene Identification by Exon Amplification. Methods in Enzymology 303:83-99.
Peters J, Siracusa LD, Pomp D, Zuberi AR, Church D, Koratkar R and Abbott CM. (1998) Encyclopedia of the Mouse Genome VII. Chromosome 2. Mammalian Genome spec. no. S: 27-49.
Cooper PR, Nowak NJ, Higgins MJ, Church DM, and Shows TB. (1998) Transcript Mapping of the Human Chromosome 11q12-q13.1 Gene-Rich Region Identifies Several Newly Described Conserved Genes. Genomics 49(3): 419-429.
Pribill I, Barnes GT, Chen J, Church D, Buckler A, Baxendale S, Bates GP, Lehrach H, Gussella MJ, Duyao MP, Ambrose CM, Gusella JF and MacDonald ME. (1997) Exon Trapping and Sequence-Based methods of Gene Finding in Transcript Mapping of Human 4p16.3. Somatic Cell and Molecular Genetics 23(6): 413-427.
McPherson JD, Apostol B, Wagner-McPherson CB, Hakim S, Del Mastro RG, Aziz N, Baer E, Gonzales G, Krane MC, Markovich R, Masny P, Ortega M, Vu J, Vujicic M, Church DM, Segal A, Grady DL, Moyzis RK, Spence MA, Lovett M and Wasmuth JJ. (1997) A Radiation Hybrid Map of Human Chromosome 5 with Integration of Cytogenetic, Genetic and Transcript Maps. Genome Research 7(9): 897-909.
Church DM, Yang J, Bocian M, Shiang R and Wasmuth JJ. (1997) A High-Resolution Physical and Transcript map of the Cri du chat Region of Human Chromosome 5p. Genome Research 7(8): 787-801.
Murthy AE, Bernards A, Church D, Wasmuth J and Gusella JF (1996) Identification and Characterization of Two Novel TPR Containing Genes. DNA Cell Biology 15(9): 727-735.
Brill S, Li S, Lyman CW, Church DM, Wasmuth JJ, Weissbach L, Bernards A and Snijders AJ. (1996) RasGAP-Related Human IQGAP2 Harbors a Potential Actin Binding Domain and Interacts with Calmodulin and Rho Family of GTPases. Molecular and Cellular Biology 16(9): 4869-4878.
Church DM, Bengtsson U, Wang K, Wasmuth JJ and Niebuhr E. (1995) Molecular Definition of Deletions of Different Segments of Distal 5p that Result in Distinct Phenotypic Features. American Journal of Human Genetics 56(5): 1162-1172.
Shiang R, Thompson LM, Zhu Y-Z, Church DM, Fielder TJ, Bocian M, Winokur ST and Wasmuth JJ. (1994) Mutations in the Transmembrane Domain of FGFR3 Cause the Most Common Genetic Form of Dwarfism, Achondroplasia. Cell 78(2): 335-342.
Church DM, Stotler CJ, Rutter JL, Murrell JR, Trofatter JA, and Buckler AJ. (1994) Isolation of Genes from Complex Sources of Mammalian Genomic DNA Using Exon Amplification. Nature Genetics 6(1): 98-105.
Church DM, Banks LT, Rogers A, Gusella JF, Housman DE, and Buckler AJ. (1994) Identification of Human Chromosome 9 Specific Genes Using Exon Amplification. Human molecular Genetics 2(11): 1915-1920.
North MA, Sanseau P, Buckler AJ, Church D, Jackson A, Patel K, Trowsdale J and Lehrach H. (1993) Efficiency and Specificity of Gene Isolation by Exon Amplification. Mammalian Genome 4(9): 466-474.
Duyao MP, Taylor SAM, Buckler AJ, Ambrose CM, Lin C, Groot N, Church D, Barnes G, Wasmuth JJ, Housman DE, MacDonald ME and Gusella JF. (1993) A Gene from Chromosome 4p16.3 with Similarity to a Superfamily of Transporter Proteins. Human Molecular Genetics 2(6): 673-676.
Ambrose C, James M, Barnes G, Lin C, Bates G, Altherr M, Duyao M, Groot N, Church D, Wasmuth JJ, Lehrach H, Housman DE, Buckler A, Gusella JF and MacDonald ME. (1993) A Novel G Protein-Coupled Receptor Kinase Maps to the Huntington’s Disease Candidate Region. Human Molecular Genetics 1(9): 697-703.
The Huntington’s Disease Collaborative Research Group. (1993) A Novel Gene Containing a Trinucleotide Repeat that is Expanded and Unstable in Huntington’s Disease Chromosomes. Cell 72: 971-983.
Taylor SAM, Snell R, Buckler AJ, Ambrose C, Duyao M, Church D, Lin CS, Altherr M, Bates GP, Groot N, Barnes G, Shaw DJ, Lehrach H, Wasmuth JJ, Harper PS, Housman DE, MacDonald ME, and Gusella JF. (1992) Cloning of the a-Adducin Gene from the Huntington’s Disease Candidate Region on Chromosome 4 by Exon Amplification. Nature Genetics 2(3): 223-227.
Brook JK, McCurrach ME, Harley HG, Buckler AJ, Church D, Aburatani H, Hunter K, Stanton VP, Thirion JP, Hudson T, Sohn R, Zemelman B, Snell R, Rindle S, Crow S, Davies J, Shelburne P, Buxton J, Jones C, Juvonen V, Johnson K, Harper PS, Shaw DJ and Housman DE. (1992) Molecular Basis of Myotonic Dystrophy: Expansion of a Trinucleotide Repeat at the 3’ End of a Transcript Encoding a Protein Kinase Family Member. Cell 68: 799-808.
Burke D and Church D. (1991) Protein Synthesis Requirements for Nuclear Division, Cytokinesis and Cell Separation in Saccharomyces cerevisiae. Molecular and Cellular Biology 11(7): 3691-3698.